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Open AccessArticle

An Au Nanofilm-Graphene/D-Type Fiber Surface Plasmon Resonance Sensor for Highly Sensitive Specificity Bioanalysis

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Collaborative Innovation Center of Light Manipulations and Applications in Universities of Shandong School of Physics and Electronics, Shandong Normal University, Jinan 250014, China
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Shandong Key Laboratory of Medical Physics and Image Processing & Shandong Provincial Engineering and Technical Center of Light Manipulations, Jinan 250014, China
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Qilu Institute of Technology, Jinan 250200, China
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Authors to whom correspondence should be addressed.
Sensors 2020, 20(4), 991; https://doi.org/10.3390/s20040991
Received: 7 January 2020 / Revised: 6 February 2020 / Accepted: 9 February 2020 / Published: 12 February 2020
A highly sensitive Au-graphene structure D-type fiber surface plasmon resonance biosensor is presented in this study to specifically detect biomolecules. The method of growing graphene is employed directly on the copper, and then a gold film of optimum thickness is sputtered, and the copper foil is etched to obtain the structure. This method makes the contact closer between the gold layer and the graphene layer to improve surface plasmon resonance performance. The performance of this type of surface plasmon resonance (SPR) sensor has been previously verified both theoretically and experimentally. With the proposed Au-graphene structure D-type fiber biosensor, the SPR behaviors are obtained and discussed. In the detection of ethanol solution, a red shift of 40 nm is found between the refractive index of 1.3330 and 1.3657. By calculation, the sensitivity of the sensor we designed is 1223 nm/RIU. Besides, the proposed sensor can detect the nucleotide bonding between the double-stranded DNA helix structures. Thus, our sensors can distinguish between mismatched DNA sequences. View Full-Text
Keywords: surface plasmon resonance biosensor; D-type plastic fiber; Au-graphene structure; high sensitivity; specificity detection surface plasmon resonance biosensor; D-type plastic fiber; Au-graphene structure; high sensitivity; specificity detection
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MDPI and ACS Style

Xi, X.; Xu, J.; Li, S.; Song, J.; Yang, W.; Sun, Y.; Jiang, S.; Han, Y.; Fan, X. An Au Nanofilm-Graphene/D-Type Fiber Surface Plasmon Resonance Sensor for Highly Sensitive Specificity Bioanalysis. Sensors 2020, 20, 991.

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