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Chiroptical Sensing: A Conceptual Introduction

1
Department of Organic Chemistry, University of Vigo, 36310 Vigo, Spain
2
Department of Food Science and Technology, Biotechnical Faculty, University of Ljubljana, Kongresni trg 12, 1000 Ljubljana, Slovenia
3
Department of Biological & Chemical Sciences, New York Institute of Technology, New York, NY 10023, USA
*
Authors to whom correspondence should be addressed.
Sensors 2020, 20(4), 974; https://doi.org/10.3390/s20040974
Received: 14 January 2020 / Revised: 7 February 2020 / Accepted: 9 February 2020 / Published: 12 February 2020
Chiroptical responses have been an essential tool over the last decades for chemical structural elucidation due to their exceptional sensitivity to geometry and intermolecular interactions. In recent times, there has been an increasing interest in the search for more efficient sensing by the rational design of tailored chiroptical systems. In this review article, advances made in chiroptical systems towards their implementation in sensing applications are summarized. Strategies to generate chiroptical responses are illustrated. Theoretical approaches to assist in the design of these systems are discussed. The development of efficient chiroptical reporters in different states of matter, essential for the implementation in sensing devises, is reviewed. In the last part, remarkable examples of chiroptical sensing applications are highlighted. View Full-Text
Keywords: chiroptical systems; theoretical simulations; chiral design; sensing applications chiroptical systems; theoretical simulations; chiral design; sensing applications
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MDPI and ACS Style

Ozcelik, A.; Pereira-Cameselle, R.; Poklar Ulrih, N.; Petrovic, A.G.; Alonso-Gómez, J.L. Chiroptical Sensing: A Conceptual Introduction. Sensors 2020, 20, 974.

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