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Applications of Graphene Quantum Dots in Biomedical Sensors

Technical University of Berlin, Straße des 17. Juni 124, 10623 Berlin, Germany
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Author to whom correspondence should be addressed.
Sensors 2020, 20(4), 1072; https://doi.org/10.3390/s20041072
Received: 25 January 2020 / Revised: 12 February 2020 / Accepted: 13 February 2020 / Published: 16 February 2020
(This article belongs to the Special Issue Nanoimmunosensor)
Due to the proliferative cancer rates, cardiovascular diseases, neurodegenerative disorders, autoimmune diseases and a plethora of infections across the globe, it is essential to introduce strategies that can rapidly and specifically detect the ultralow concentrations of relevant biomarkers, pathogens, toxins and pharmaceuticals in biological matrices. Considering these pathophysiologies, various research works have become necessary to fabricate biosensors for their early diagnosis and treatment, using nanomaterials like quantum dots (QDs). These nanomaterials effectively ameliorate the sensor performance with respect to their reproducibility, selectivity as well as sensitivity. In particular, graphene quantum dots (GQDs), which are ideally graphene fragments of nanometer size, constitute discrete features such as acting as attractive fluorophores and excellent electro-catalysts owing to their photo-stability, water-solubility, biocompatibility, non-toxicity and lucrativeness that make them favorable candidates for a wide range of novel biomedical applications. Herein, we reviewed about 300 biomedical studies reported over the last five years which entail the state of art as well as some pioneering ideas with respect to the prominent role of GQDs, especially in the development of optical, electrochemical and photoelectrochemical biosensors. Additionally, we outline the ideal properties of GQDs, their eclectic methods of synthesis, and the general principle behind several biosensing techniques. View Full-Text
Keywords: graphene quantum dots (GQDs); nanomaterials; biosensors; optical sensors; electrochemical sensors; photoelectrochemical sensors; biomedical applications graphene quantum dots (GQDs); nanomaterials; biosensors; optical sensors; electrochemical sensors; photoelectrochemical sensors; biomedical applications
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MDPI and ACS Style

Mansuriya, B.D.; Altintas, Z. Applications of Graphene Quantum Dots in Biomedical Sensors. Sensors 2020, 20, 1072.

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