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Erratum published on 26 July 2019, see Sensors 2019, 19(15), 3288.
Review

Biosensors for Epilepsy Management: State-of-Art and Future Aspects

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Department of Chemistry, School of Basic and Applied Sciences, Galgotias University, Greater Noida, Gautam Buddh Nagar, Uttar Pradesh 201308, India
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School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India
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Bio-MEMS and Microsystems Laboratory, Department of Electrical and Computer, Engineering, Florida International University, Miami, FL 33174, USA
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Functional Nanomaterials, Institute for Materials Science, Kiel University, Kaiserstr 2, D-24143 Kiel, Germany
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Department of Immunology and Nano-Medicine, Institute of NeuroImmune Pharmacology, Center for Personalized Nanomedicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33199, USA
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School of Life Sciences, Beijing Institute of Technology, Beijing 100081, China
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College of Chemistry and Materials Science, Northwest University, Xi’an 710069, Shaanxi, China
*
Authors to whom correspondence should be addressed.
Sensors 2019, 19(7), 1525; https://doi.org/10.3390/s19071525
Received: 11 March 2019 / Revised: 24 March 2019 / Accepted: 25 March 2019 / Published: 28 March 2019
(This article belongs to the Section Biosensors)
Epilepsy is a serious neurological disorder which affects every aspect of patients’ life, including added socio-economic burden. Unfortunately, only a few suppressive medicines are available, and a complete cure for the disease has not been found yet. Excluding the effectiveness of available therapies, the timely detection and monitoring of epilepsy are of utmost priority for early remediation and prevention. Inability to detect underlying epileptic signatures at early stage causes serious damage to the central nervous system (CNS) and irreversible detrimental variations in the organ system. Therefore, development of a multi-task solving novel smart biosensing systems is urgently required. The present review highlights advancements in state-of-art biosensing technology investigated for epilepsy diseases diagnostics and progression monitoring or both together. State of art epilepsy biosensors are composed of nano-enabled smart sensing platform integrated with micro/electronics and display. These diagnostics systems provide bio-information needed to understand disease progression and therapy optimization timely. The associated challenges related to the development of an efficient epilepsy biosensor and vision considering future prospects are also discussed in this report. This review will serve as a guide platform to scholars for understanding and planning of future research aiming to develop a smart bio-sensing system to detect and monitor epilepsy for point-of-care (PoC) applications. View Full-Text
Keywords: nanotechnology; biosensors; neurodegenerative disorder (NDD); diagnostics; analytical tools; diseases management nanotechnology; biosensors; neurodegenerative disorder (NDD); diagnostics; analytical tools; diseases management
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MDPI and ACS Style

Tiwari, S.; Sharma, V.; Mujawar, M.; Mishra, Y.K.; Kaushik, A.; Ghosal, A. Biosensors for Epilepsy Management: State-of-Art and Future Aspects. Sensors 2019, 19, 1525. https://doi.org/10.3390/s19071525

AMA Style

Tiwari S, Sharma V, Mujawar M, Mishra YK, Kaushik A, Ghosal A. Biosensors for Epilepsy Management: State-of-Art and Future Aspects. Sensors. 2019; 19(7):1525. https://doi.org/10.3390/s19071525

Chicago/Turabian Style

Tiwari, Shivani, Varsha Sharma, Mubarak Mujawar, Yogendra Kumar Mishra, Ajeet Kaushik, and Anujit Ghosal. 2019. "Biosensors for Epilepsy Management: State-of-Art and Future Aspects" Sensors 19, no. 7: 1525. https://doi.org/10.3390/s19071525

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