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Article

Optical-Spectrometry-Based Method for Immunosuppressant Medicine Level Detection in Aqueous Solutions

1
Department of Metrology and Optoelectronics, Faculty of Electronics, Telecommunications and Informatics, Gdańsk University of Technology, 11/12 Narutowicza Street, 80-233 Gdansk, Poland
2
Department of Nephrology, Transplantology and Internal Diseases, Faculty of Medicine, Medical University of Gdańsk, 3a Marii Skłodowskiej-Curie Street, 80-210 Gdansk, Poland
3
Department of Morphological Sciences, Faculty of Veterinary Medicine, Warsaw University of Life Sciences, 159 Nowoursynowska Street, 02-776 Warszawa, Poland
*
Authors to whom correspondence should be addressed.
Sensors 2018, 18(7), 2001; https://doi.org/10.3390/s18072001
Received: 15 May 2018 / Revised: 19 June 2018 / Accepted: 20 June 2018 / Published: 22 June 2018
(This article belongs to the Special Issue Spectroscopy Based Sensors)
In this paper, an investigation into detecting immunosuppressive medicine in aqueous solutions using a spectrometry-based technique is described. Using optical transmissive spectrometry, absorbance measurements in the spectra range from 250 nm to 1000 nm were carried out for different cyclosporine A (CsA) concentrations in aqueous solutions. The experiment was conducted for samples both with and without interferent substances—glucose and sodium chloride. Using a dedicated algorithm, the measured data was analyzed and a high correlation coefficient R2 = 0.8647 was achieved. The experiment showed that the described technique allowed for the detection of various CsA concentration levels in a selective, label-free and simple way. This method could be used in medicine, veterinary medicine and laboratory diagnostics. View Full-Text
Keywords: optical spectrophotometry; label-free detection; cyclosporine optical spectrophotometry; label-free detection; cyclosporine
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MDPI and ACS Style

Marzejon, M.; Kosowska, M.; Majchrowicz, D.; Bułło-Piontecka, B.; Wąsowicz, M.; Jędrzejewska-Szczerska, M. Optical-Spectrometry-Based Method for Immunosuppressant Medicine Level Detection in Aqueous Solutions. Sensors 2018, 18, 2001. https://doi.org/10.3390/s18072001

AMA Style

Marzejon M, Kosowska M, Majchrowicz D, Bułło-Piontecka B, Wąsowicz M, Jędrzejewska-Szczerska M. Optical-Spectrometry-Based Method for Immunosuppressant Medicine Level Detection in Aqueous Solutions. Sensors. 2018; 18(7):2001. https://doi.org/10.3390/s18072001

Chicago/Turabian Style

Marzejon, Marcin, Monika Kosowska, Daria Majchrowicz, Barbara Bułło-Piontecka, Michał Wąsowicz, and Małgorzata Jędrzejewska-Szczerska. 2018. "Optical-Spectrometry-Based Method for Immunosuppressant Medicine Level Detection in Aqueous Solutions" Sensors 18, no. 7: 2001. https://doi.org/10.3390/s18072001

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