Next Article in Journal
Hydrodynamic Tweezers: Trapping and Transportation in Microscale Using Vortex Induced by Oscillation of a Single Piezoelectric Actuator
Next Article in Special Issue
Hydrogen Sulfide Gas Detection via Multivariate Optical Computing
Previous Article in Journal
A Correction Approach for the Inclined Array of Hydrophones in Synthetic Aperture Sonar
Previous Article in Special Issue
Nitric Oxide Analysis Down to ppt Levels by Optical-Feedback Cavity-Enhanced Absorption Spectroscopy
Article Menu
Issue 7 (July) cover image

Export Article

Open AccessArticle

Optical-Spectrometry-Based Method for Immunosuppressant Medicine Level Detection in Aqueous Solutions

1
Department of Metrology and Optoelectronics, Faculty of Electronics, Telecommunications and Informatics, Gdańsk University of Technology, 11/12 Narutowicza Street, 80-233 Gdansk, Poland
2
Department of Nephrology, Transplantology and Internal Diseases, Faculty of Medicine, Medical University of Gdańsk, 3a Marii Skłodowskiej-Curie Street, 80-210 Gdansk, Poland
3
Department of Morphological Sciences, Faculty of Veterinary Medicine, Warsaw University of Life Sciences, 159 Nowoursynowska Street, 02-776 Warszawa, Poland
*
Authors to whom correspondence should be addressed.
Sensors 2018, 18(7), 2001; https://doi.org/10.3390/s18072001
Received: 15 May 2018 / Revised: 19 June 2018 / Accepted: 20 June 2018 / Published: 22 June 2018
(This article belongs to the Special Issue Spectroscopy Based Sensors)
  |  
PDF [2334 KB, uploaded 22 June 2018]
  |  

Abstract

In this paper, an investigation into detecting immunosuppressive medicine in aqueous solutions using a spectrometry-based technique is described. Using optical transmissive spectrometry, absorbance measurements in the spectra range from 250 nm to 1000 nm were carried out for different cyclosporine A (CsA) concentrations in aqueous solutions. The experiment was conducted for samples both with and without interferent substances—glucose and sodium chloride. Using a dedicated algorithm, the measured data was analyzed and a high correlation coefficient R2 = 0.8647 was achieved. The experiment showed that the described technique allowed for the detection of various CsA concentration levels in a selective, label-free and simple way. This method could be used in medicine, veterinary medicine and laboratory diagnostics. View Full-Text
Keywords: optical spectrophotometry; label-free detection; cyclosporine optical spectrophotometry; label-free detection; cyclosporine
Figures

Graphical abstract

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
SciFeed

Share & Cite This Article

MDPI and ACS Style

Marzejon, M.; Kosowska, M.; Majchrowicz, D.; Bułło-Piontecka, B.; Wąsowicz, M.; Jędrzejewska-Szczerska, M. Optical-Spectrometry-Based Method for Immunosuppressant Medicine Level Detection in Aqueous Solutions. Sensors 2018, 18, 2001.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Sensors EISSN 1424-8220 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top