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Sensors 2018, 18(10), 3295;

Optical Micro/Nanofiber-Based Localized Surface Plasmon Resonance Biosensors: Fiber Diameter Dependence

Guangdong Key Laboratory of Optical Fiber Sensing and Communications, Institute of Photonics Technology, Jinan University, Guangzhou 510632, China
State Key Laboratory of Applied Optics, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun 130033, China
XLIM Research Institute, UMR 7252 CNRS/University of Limoges, 87060 Limoges CEDEX, France
Authors to whom correspondence should be addressed.
Received: 19 August 2018 / Revised: 18 September 2018 / Accepted: 26 September 2018 / Published: 30 September 2018
(This article belongs to the Special Issue Surface Plasmon Resonance Sensing 2019)
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Integration of functional nanomaterials with optical micro/nanofibers (OMNFs) can bring about novel optical properties and provide a versatile platform for various sensing applications. OMNFs as the key element, however, have seldom been investigated. Here, we focus on the optimization of fiber diameter by taking micro/nanofiber-based localized surface plasmon resonance sensors as a model. We systematically study the dependence of fiber diameter on the sensing performance of such sensors. Both theoretical and experimental results show that, by reducing fiber diameter, the refractive index sensitivity can be significantly increased. Then, we demonstrate the biosensing capability of the optimized sensor for streptavidin detection and achieve a detection limit of 1 pg/mL. Furthermore, the proposed theoretical model is applicable to other nanomaterials and OMNF-based sensing schemes for performance optimization. View Full-Text
Keywords: localized surface plasmon resonance; fiber optic biosensor; optical micro/nanofiber localized surface plasmon resonance; fiber optic biosensor; optical micro/nanofiber

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Li, K.; Zhou, W.; Zeng, S. Optical Micro/Nanofiber-Based Localized Surface Plasmon Resonance Biosensors: Fiber Diameter Dependence. Sensors 2018, 18, 3295.

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