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Open AccessArticle

Flexible, Low-Cost Sensor Based on Electrolyte Gated Carbon Nanotube Field Effect Transistor for Organo-Phosphate Detection

1
Department of Electrical Engineering and Information Technology, Institute for Nanoelectronics, Technische Universität München, Munich 80333, Germany
2
Faculty of Science and Technology, Free University of Bozen-Bolzano, 39100 Bolzano, Italy
*
Author to whom correspondence should be addressed.
Academic Editors: Paolo Scopece, Ligia Moretto and Paolo Ugo
Sensors 2017, 17(5), 1147; https://doi.org/10.3390/s17051147
Received: 4 April 2017 / Revised: 28 April 2017 / Accepted: 15 May 2017 / Published: 18 May 2017
(This article belongs to the Special Issue Advanced Sensors Based on Carbon Electrodes)
A flexible enzymatic acetylcholinesterase biosensor based on an electrolyte-gated carbon nanotube field effect transistor is demonstrated. The enzyme immobilization is done on a planar gold gate electrode using 3-mercapto propionic acid as the linker molecule. The sensor showed good sensing capability as a sensor for the neurotransmitter acetylcholine, with a sensitivity of 5.7 μA/decade, and demonstrated excellent specificity when tested against interfering analytes present in the body. As the flexible sensor is supposed to suffer mechanical deformations, the endurance of the sensor was measured by putting it under extensive mechanical stress. The enzymatic activity was inhibited by more than 70% when the phosphate-buffered saline (PBS) buffer was spiked with 5 mg/mL malathion (an organophosphate) solution. The biosensor was successfully challenged with tap water and strawberry juice, demonstrating its usefulness as an analytical tool for organophosphate detection. View Full-Text
Keywords: carbon nanotube; flexible; electrolyte gated transistor; organophosphate detection carbon nanotube; flexible; electrolyte gated transistor; organophosphate detection
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Bhatt, V.D.; Joshi, S.; Becherer, M.; Lugli, P. Flexible, Low-Cost Sensor Based on Electrolyte Gated Carbon Nanotube Field Effect Transistor for Organo-Phosphate Detection. Sensors 2017, 17, 1147.

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