Next Article in Journal
Previous Article in Journal
[N,N′-Di-tert-butyl-P,P-diphenylphosphinimidic Amidato-κNN′]chlorosilicon-κSi-tetracarbonyliron
Short Note

Methyl 2-((3-(3-methoxyphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)thio)acetate

Faculty of Food Technology Osijek, Josip Juraj Strossmayer University of Osijek, Franje Kuhača 18, 31000 Osijek, Croatia
Faculty of Chemistry and Technology, University of Split, R. Boškovića 35, 21000 Split, Croatia
Author to whom correspondence should be addressed.
Academic Editor: R. Alan Aitken
Molbank 2022, 2022(3), M1434;
Received: 2 August 2022 / Revised: 22 August 2022 / Accepted: 23 August 2022 / Published: 25 August 2022
A green synthetic procedure was developed for the two-step synthesis of methyl 2-((3-(3-methoxyphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)thio)acetate from anthranilic acid, using two green chemistry approaches: utilization of the DES and microwave-induced synthesis. The first step includes a synthesis of 2-mercapto-3-(3-methoxyphenyl)quinazolin-4(3H)-one which was performed in choline chloride:urea DES. In the second step S-alkylation of 2-mercapto-3-(3-methoxyphenyl)quinazolin-4(3H)-one was performed in a microwave-induced reaction. The desired compound was successfully obtained in a yield of 59% and was characterized by different spectral methods. View Full-Text
Keywords: quinazolinone; green chemistry; alkylation quinazolinone; green chemistry; alkylation
Show Figures

Figure 1

MDPI and ACS Style

Molnar, M.; Komar, M.; Jerković, I. Methyl 2-((3-(3-methoxyphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)thio)acetate. Molbank 2022, 2022, M1434.

AMA Style

Molnar M, Komar M, Jerković I. Methyl 2-((3-(3-methoxyphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)thio)acetate. Molbank. 2022; 2022(3):M1434.

Chicago/Turabian Style

Molnar, Maja, Mario Komar, and Igor Jerković. 2022. "Methyl 2-((3-(3-methoxyphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)thio)acetate" Molbank 2022, no. 3: M1434.

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

Back to TopTop