Next Article in Journal
Previous Article in Journal
An Efficient Synthesis of Novel 3-[(Heteroaryl-2-ylimino)-methyl]-4-hydroxy-chromen-2-ones and Analogue of Tetrazole Derivatives and Their Antibacterial Activity
Short Note

2-(2-(4-Methoxyphenyl)-4,9-dimethyl-7-oxo-7H-furo[2,3-f]chromen-3-yl)acetic Acid

N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Science, Leninsky Pr., 47, 119991 Moscow, Russia
Author to whom correspondence should be addressed.
Academic Editors: Oleg A. Rakitin and Fawaz Aldabbagh
Molbank 2021, 2021(4), M1304;
Received: 12 November 2021 / Revised: 30 November 2021 / Accepted: 6 December 2021 / Published: 9 December 2021
(This article belongs to the Section Organic Synthesis)
For the first time, we describe a new approach towards the synthesis of previously unknown 2-(2-(4-methoxyphenyl)-4,9-dimethyl-7-oxo-7H-furo[2,3-f]chromen-3-yl)acetic acid. The presented method is based on the multicomponent condensation of 5-hydroxy-4,7-dimethyl-2H-chromen-2-one, 4-methoxyphenylglyoxal and Meldrum’s acid. It was shown that the studied reaction proceeds in two steps including the initial interaction of starting materials in MeCN and the final formation of furylacetic acid moiety in acidic media. The structures of the obtained compound were established by 1H, 13C-NMR spectroscopy and high-resolution mass spectrometry. View Full-Text
Keywords: multicomponent reaction; furocoumarin; Meldrum’s acid; arylglyoxals multicomponent reaction; furocoumarin; Meldrum’s acid; arylglyoxals
Show Figures

Graphical abstract

MDPI and ACS Style

Lichitsky, B.V.; Komogortsev, A.N.; Melekhina, V.G. 2-(2-(4-Methoxyphenyl)-4,9-dimethyl-7-oxo-7H-furo[2,3-f]chromen-3-yl)acetic Acid. Molbank 2021, 2021, M1304.

AMA Style

Lichitsky BV, Komogortsev AN, Melekhina VG. 2-(2-(4-Methoxyphenyl)-4,9-dimethyl-7-oxo-7H-furo[2,3-f]chromen-3-yl)acetic Acid. Molbank. 2021; 2021(4):M1304.

Chicago/Turabian Style

Lichitsky, Boris V., Andrey N. Komogortsev, and Valeriya G. Melekhina. 2021. "2-(2-(4-Methoxyphenyl)-4,9-dimethyl-7-oxo-7H-furo[2,3-f]chromen-3-yl)acetic Acid" Molbank 2021, no. 4: M1304.

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

Back to TopTop