Next Article in Journal
CF3-Bis-TEMPO-Vis: New Visible Light Active Bis-Benzimidazolequinone Alkoxyamine
Previous Article in Journal
Bis(pyrazol-1-yl)methane-4,4′-dicarboxylic Acid
Short Note

11H-Indeno[1,2-b]quinoxalin-11-one 2-(4-ethylbenzylidene)hydrazone

1
Kizhner Research Center, Tomsk Polytechnic University, 634050 Tomsk, Russia
2
Scientific Research Institute of Biological Medicine, Altai State University, 656049 Barnaul, Russia
*
Author to whom correspondence should be addressed.
Academic Editor: Ian R. Baxendale
Molbank 2021, 2021(4), M1299; https://doi.org/10.3390/M1299
Received: 9 October 2021 / Revised: 16 November 2021 / Accepted: 19 November 2021 / Published: 23 November 2021
(This article belongs to the Section Organic Synthesis)
11H-Indeno[1,2-b]quinoxaline derivatives present an important type of nitrogen-containing heterocyclic compound that are useful intermediate products in organic synthesis and have potential pharmaceutical applications. A new 11H-indeno[1,2-b]quinoxalin-11-one-2-(4-ethylbenzylidene)hydrazone (compound 3) was synthesized. Compound 3 is the first example of an azine derivative based on the 11H-indeno[1,2-b]quinoxaline system. The Z,E-isomerism of compound 3 was investigated by DFT calculations. Bioavailability was evaluated in silico using ADME predictions. According to the ADME results, compound 3 is potentially highly bioavailable and has potential to be used for the treatment of neuroinflammation and ischemia–reperfusion injury. View Full-Text
Keywords: azine; aldazine; 11H-indeno[1,2-b]quinoxalin-11-one; DFT; ADME azine; aldazine; 11H-indeno[1,2-b]quinoxalin-11-one; DFT; ADME
Show Figures

Figure 1

MDPI and ACS Style

Kovrizhina, A.R.; Samorodova, E.I.; Khlebnikov, A.I. 11H-Indeno[1,2-b]quinoxalin-11-one 2-(4-ethylbenzylidene)hydrazone. Molbank 2021, 2021, M1299. https://doi.org/10.3390/M1299

AMA Style

Kovrizhina AR, Samorodova EI, Khlebnikov AI. 11H-Indeno[1,2-b]quinoxalin-11-one 2-(4-ethylbenzylidene)hydrazone. Molbank. 2021; 2021(4):M1299. https://doi.org/10.3390/M1299

Chicago/Turabian Style

Kovrizhina, Anastasia R., Elizaveta I. Samorodova, and Andrei I. Khlebnikov 2021. "11H-Indeno[1,2-b]quinoxalin-11-one 2-(4-ethylbenzylidene)hydrazone" Molbank 2021, no. 4: M1299. https://doi.org/10.3390/M1299

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop