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Communication

Novel Synthesis of N-Acetylcysteine Medicine Using an Effective Method

1
Graduate School of Biomedical Engineering, University of New South Wales, Sydney, NSW 2052, Australia
2
School of Science, UNSW Canberra, Northcott Drive, Canberra, ACT 2610, Australia
*
Authors to whom correspondence should be addressed.
Academic Editor: Hideto Miyabe
Molbank 2021, 2021(4), M1288; https://doi.org/10.3390/M1288
Received: 15 August 2021 / Revised: 7 September 2021 / Accepted: 8 October 2021 / Published: 13 October 2021
N-acetylcysteine (NAC) is mainly administrated as a mucolytic medication, antioxidant supplement, antidote in paracetamol overdose, and a drug for the prevention of diabetic kidney disease. Its effect has been investigated for the treatment of several diseases such as COVID-19. In this work, an effective method for high-yield synthesis of N-acetylcysteine is proposed. This drug can be synthesized in a single-batch step instead of using a multi-stage process. The proposed method has shown the potential to be considered as an alternative method for producing NAC. The purification process was carried out using suitable solvents to reach a high level of purity. The characterization of the synthesized drug was undertaken through Elemental analysis, Proton Nuclear Magnetic Resonance (1H NMR), High Performance Liquid Chromatography (HPLC), Fourier Transform Infrared Spectroscopy (FT-IR), and melting point analyses. View Full-Text
Keywords: N-acetylcysteine (NAC); drug synthesis; lung anti-inflammatory; cough medicine; antioxidant; pharmaceutical supplement; characterization N-acetylcysteine (NAC); drug synthesis; lung anti-inflammatory; cough medicine; antioxidant; pharmaceutical supplement; characterization
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MDPI and ACS Style

Ziaee, F.; Ziaee, M. Novel Synthesis of N-Acetylcysteine Medicine Using an Effective Method. Molbank 2021, 2021, M1288. https://doi.org/10.3390/M1288

AMA Style

Ziaee F, Ziaee M. Novel Synthesis of N-Acetylcysteine Medicine Using an Effective Method. Molbank. 2021; 2021(4):M1288. https://doi.org/10.3390/M1288

Chicago/Turabian Style

Ziaee, Farzaneh, and Mohammad Ziaee. 2021. "Novel Synthesis of N-Acetylcysteine Medicine Using an Effective Method" Molbank 2021, no. 4: M1288. https://doi.org/10.3390/M1288

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