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Short Note

2-Oxo-2H-chromen-7-yl 4-chlorobenzoate

Escuela de Ciencias Química, Facultad de Ciencias, Universidad Pedagógica y Tecnológica de Colombia, Avenida Central del Norte 39-115, Tunja 150003, Colombia
Bioorganic Compounds Research Group, Department of Chemistry, Universidad de los Andes, Carrera 1 No. 18A-10, Bogotá 111711, Colombia
Authors to whom correspondence should be addressed.
Academic Editor: Giovanni Ribaudo
Molbank 2021, 2021(3), M1279;
Received: 29 August 2021 / Revised: 5 September 2021 / Accepted: 10 September 2021 / Published: 14 September 2021
(This article belongs to the Special Issue Synthesis of Flavonoids or Other Nature-Inspired Small Molecules)
We describe the synthesis of 2-oxo-2H-chromen-7-yl 4-chlorobenzoate 3 in 88% yield by the O-acylation reaction of 7-hydroxy-2H-chromen-2-one 1 with 4-chlorobenzoyl chloride 2 in dichloromethane using a slight excess of triethylamine at 20 °C for 1 h. The ester 3 was completely characterized by mass spectrometry, IR, UV–Vis, 1D, and 2D NMR spectroscopy. View Full-Text
Keywords: 7-hydroxy-2H-chromen-2-one; O-acylation reaction; coumarin 7-hydroxy-2H-chromen-2-one; O-acylation reaction; coumarin
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MDPI and ACS Style

Becerra, D.; Portilla, J.; Castillo, J.-C. 2-Oxo-2H-chromen-7-yl 4-chlorobenzoate. Molbank 2021, 2021, M1279.

AMA Style

Becerra D, Portilla J, Castillo J-C. 2-Oxo-2H-chromen-7-yl 4-chlorobenzoate. Molbank. 2021; 2021(3):M1279.

Chicago/Turabian Style

Becerra, Diana, Jaime Portilla, and Juan-Carlos Castillo. 2021. "2-Oxo-2H-chromen-7-yl 4-chlorobenzoate" Molbank 2021, no. 3: M1279.

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