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(1R,4S,5S)-5-((3-Hydroxypropyl)amino)-4-((1-methyl-1H-tetrazol-5-yl)thio)cyclopent-2-en-1-ol

Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003 Lisboa, Portugal
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Academic Editors: Dimitrios Matiadis and Eleftherios Halevas
Molbank 2021, 2021(2), M1199; https://doi.org/10.3390/M1199 (registering DOI)
Received: 14 March 2021 / Revised: 26 March 2021 / Accepted: 27 March 2021 / Published: 1 April 2021
Using environmentally friendly conditions, the nucleophilic ring-opening reaction of 6-azabicyclo[3.1.0]hex-3-en-2-ol with 1-methyl-1H-tetrazole-5-thiol provided a novel thiol-incorporated aminocyclopentitol, (1R,4S,5S)-5-((3-hydroxypropyl)amino)-4-((1-methyl-1H-tetrazol-5-yl)thio)cyclopent-2-en-1-ol, in excellent yield (95%). The newly synthesized compound was analyzed and characterized via 1H, 13C-NMR, HSQC, and mass spectral data. View Full-Text
Keywords: aminocyclopentitol; bicyclic aziridine; water chemistry; nucleophilic substitution aminocyclopentitol; bicyclic aziridine; water chemistry; nucleophilic substitution
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MDPI and ACS Style

Fortunato, M.A.G.; Siopa, F.; Afonso, C.A.M. (1R,4S,5S)-5-((3-Hydroxypropyl)amino)-4-((1-methyl-1H-tetrazol-5-yl)thio)cyclopent-2-en-1-ol. Molbank 2021, 2021, M1199. https://doi.org/10.3390/M1199

AMA Style

Fortunato MAG, Siopa F, Afonso CAM. (1R,4S,5S)-5-((3-Hydroxypropyl)amino)-4-((1-methyl-1H-tetrazol-5-yl)thio)cyclopent-2-en-1-ol. Molbank. 2021; 2021(2):M1199. https://doi.org/10.3390/M1199

Chicago/Turabian Style

Fortunato, Milene A.G.; Siopa, Filipa; Afonso, Carlos A.M. 2021. "(1R,4S,5S)-5-((3-Hydroxypropyl)amino)-4-((1-methyl-1H-tetrazol-5-yl)thio)cyclopent-2-en-1-ol" Molbank 2021, no. 2: M1199. https://doi.org/10.3390/M1199

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