Next Article in Journal
[Dicyclohexyl(sulfanylidene)-λ5-phosphanyl]methanol
Previous Article in Journal
Synthesis and Crystal Structure of A Pyrithione Derivative: Bis{2-[(1-oxidopyridin-2-yl)sulfanyl]-4,5-dihydro-1H-imidazol-3-ium} tetrachlorocuprate(2-)
Article Menu

Export Article

Open AccessShort Note

6R/S-deutero-α-d-mannopyranoside 1-phosphate

Lennard-Jones Laboratory, School of Chemical and Physical Sciences, Keele University, Keele, Staffordshire ST5 5BG, UK
*
Author to whom correspondence should be addressed.
Current address: Department of Biological Chemistry, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK.
Molbank 2019, 2019(3), M1068; https://doi.org/10.3390/M1068
Received: 3 June 2019 / Revised: 19 June 2019 / Accepted: 24 June 2019 / Published: 27 June 2019
(This article belongs to the Special Issue Organic Synthesis of Carbohydrates)
  |  
PDF [367 KB, uploaded 27 June 2019]
  |  

Abstract

6R/S-deutero-α-d-mannopyranoside 1-phosphate was synthesised from a C6 aldehydic mannose thioglycoside donor in four steps. Using NaBD4 as the reductant, isotopic enrichment at C6 was achieved and the resultant C6-deuterated material was converted through to the glycosyl 1-phosphate using a protection/glycosylation/deprotection sequence. The product was fully characterised by 1H, 13C, 31P and 2D NMR, alongside MS analysis. View Full-Text
Keywords: mannose; glycosyl-phosphate; deuterium; isotope; NMR mannose; glycosyl-phosphate; deuterium; isotope; NMR
Figures

Graphical abstract

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

Supplementary materials

SciFeed

Share & Cite This Article

MDPI and ACS Style

Ahmadipour, S.; Miller, G.J. 6R/S-deutero-α-d-mannopyranoside 1-phosphate. Molbank 2019, 2019, M1068.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Molbank EISSN 1422-8599 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top