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Open AccessCommunication

N-Propargylation of Indolo-Triterpenoids and Their Application in Mannich Reaction

1
Ufa Institute of Chemistry UFRS RAS, Ufa 450054, 71 pr. Oktyabrya, Russia
2
Chemical Department, Bashkir State University, Ufa 450076, 32 Validy Str., Russia
*
Author to whom correspondence should be addressed.
Molbank 2019, 2019(2), M1065; https://doi.org/10.3390/M1065
Received: 16 May 2019 / Revised: 5 June 2019 / Accepted: 11 June 2019 / Published: 13 June 2019
(This article belongs to the Section Natural Products)
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Abstract

The introduction of the alkynyl moiety to the triterpenic core through a linkage to the indole nitrogen is described. The reaction of N-propargylindoles with N-methylpiperazine using Mannich reaction led to propargylaminoalkynyl-triterpenoids, whose structures were established by NMR spectroscopy. View Full-Text
Keywords: triterpenoids; indoles; N-propargylation; alkyne; Mannich reaction triterpenoids; indoles; N-propargylation; alkyne; Mannich reaction
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Khusnutdinova, E.F.; Petrova, A.V.; Bashirova, G.M.; Kazakova, O.B. N-Propargylation of Indolo-Triterpenoids and Their Application in Mannich Reaction. Molbank 2019, 2019, M1065.

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