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Department of Chemistry, Universidad del Valle, A. A. 25360 Santiago de Cali, Colombia
Author to whom correspondence should be addressed.
Molbank 2018, 2018(3), 1001;
Received: 25 May 2018 / Revised: 15 June 2018 / Accepted: 18 June 2018 / Published: 21 June 2018
(This article belongs to the Section Organic Synthesis)
PDF [581 KB, uploaded 21 June 2018]


The coumarinyl-quinolinylchalcone hybrid (E)-3-[3-(2-butoxyquinolin-3-yl)acryloyl]-2-hydroxy-4H-chromen-4-one 3b was prepared in good yield from a Claisen-Schmidt condensation reaction between 3-acetyl-4-hydroxy-2H-chromen-2-one 1 and 2-butoxyquinoline-3-carbaldehyde 2 in methanol at reflux and catalyzed by KOH pellets. The structure of the synthesized compound 3b was fully confirmed by FTIR-ATR, (1D and 2D) NMR experiments, EIMS and elemental analysis. View Full-Text
Keywords: coumarinyl-quinolinylchalcone hybrid; Claisen-Schmidt condensation coumarinyl-quinolinylchalcone hybrid; Claisen-Schmidt condensation
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Abonia, R.; Gutiérrez, L.; Quiroga, J.; Insuasty, B. (E)-3-[3-(2-Butoxyquinolin-3-yl)acryloyl]-2-hydroxy-4H-chromen-4-one. Molbank 2018, 2018, 1001.

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