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N-(4-Bromobenzyl)-2-(5,6-dimethyl-1H-benzo[d]imid-azol-2-yl)benzeneamine

1
Institute of Biochemistry and Biophysics Polish Academy of Sciences, Pawinskiego 5a, 02-106 Warsaw, Poland
2
Faculty of Chemistry, University of Warsaw, Pasteura 1, 02-093 Warsaw, Poland
3
Biological and Chemical Research Centre, University of Warsaw, Żwirki i Wigury 101, 02-089 Warsaw, Poland
4
Institute of Genetics and Biotechnology, Faculty of Biology, University of Warszaw, Pawinskiego 5a, 02-106 Warsaw, Poland
*
Author to whom correspondence should be addressed.
Molbank 2018, 2018(1), M979; https://doi.org/10.3390/M979
Received: 22 December 2017 / Revised: 26 January 2018 / Accepted: 28 January 2018 / Published: 30 January 2018
(This article belongs to the Special Issue Heterocycles)
N-(4-Bromobenzyl)-2-(5,6-dimethyl-1H-benzo[d]imidazol-2-yl)benzeneamine was obtained by condensation of N-(4-bromobenzyl)-3,1-benzoxazine-2,4-dione (N-(4-bromobenzyl)isatoic anhydride) with 4,5-dimethyl-1,2-phenylenediamine in refluxing acetic acid. This is a rare example of condensation of N-substituted 3,1-benzoxazine-2,4-dione with 1,2-phenylenediamine, which resulted in the formation of a benzimidazole derivative with a moderate yield. Crystallographic studies and initial biological screening were performed for the obtained product. View Full-Text
Keywords: substituted benzimidazoles; 3,1-benzoxazine-2,4-dione; isatoic anhydride; 1,2-phenylenediamine; crystallographic studies; cytotoxicity substituted benzimidazoles; 3,1-benzoxazine-2,4-dione; isatoic anhydride; 1,2-phenylenediamine; crystallographic studies; cytotoxicity
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MDPI and ACS Style

Dziełak, M.; Trzybiński, D.; Czerwińska, J.; Majchrzak, B.; Tudek, B.; Woźniak, K.; Mieczkowski, A. N-(4-Bromobenzyl)-2-(5,6-dimethyl-1H-benzo[d]imid-azol-2-yl)benzeneamine. Molbank 2018, 2018, M979. https://doi.org/10.3390/M979

AMA Style

Dziełak M, Trzybiński D, Czerwińska J, Majchrzak B, Tudek B, Woźniak K, Mieczkowski A. N-(4-Bromobenzyl)-2-(5,6-dimethyl-1H-benzo[d]imid-azol-2-yl)benzeneamine. Molbank. 2018; 2018(1):M979. https://doi.org/10.3390/M979

Chicago/Turabian Style

Dziełak, Monika; Trzybiński, Damian; Czerwińska, Jolanta; Majchrzak, Bartosz; Tudek, Barbara; Woźniak, Krzysztof; Mieczkowski, Adam. 2018. "N-(4-Bromobenzyl)-2-(5,6-dimethyl-1H-benzo[d]imid-azol-2-yl)benzeneamine" Molbank 2018, no. 1: M979. https://doi.org/10.3390/M979

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