4-Acetyl-2-hydroxy-2,5-dimethylfuran-3(2H)-one
1
Department of Chemistry, Graduate School of Science and Technology, Kumamoto University, Kurokami 2-39-1, Kumamoto 860-8555, Japan
2
Department of Chemistry, Kumamoto University, Kurokami 2-39-1, Kumamoto 860-8555, Japan
*
Author to whom correspondence should be addressed.
Academic Editors: Luke R. Odell and Norbert Haider
Molbank 2016, 2016(4), M913; https://doi.org/10.3390/M913
Received: 7 September 2016 / Revised: 12 October 2016 / Accepted: 14 October 2016 / Published: 20 October 2016
The facile synthesis of 4-acetyl-2-hydroxy-2,5-dimethylfuran-3(2H)-one (4) was achieved by the Mn(OAc)3-mediated aerobic oxidation of 2,4-pentanedione or the direct reaction of Mn(acac)3 in AcOH-TFE at room temperature under a dried air stream.
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Keywords:
4-acetyl-2-hydroxy-2,5-dimethylfuran-3(2H)-one; keto-hemiacetal; Mn(acac)3; Mn(OAc)3; aerobic oxidation; 2,4-pentanedione; cyclic acetal; trifluoroethanol
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- Supplementary File 1:
Supplementary 3D structure (MOL, 1 KB)
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3D structure generated by CORINA Classic by MN-AM. - Supplementary File 2:
Supplementary (INCHI, 361 B)
- Supplementary File 3:
Supplementary (MOL, 1 KB)
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- Supplementary File 4:
Supplementary (PDF, 1776 KB)
MDPI and ACS Style
Akazaki, C.; Kawabata, S.; Nishino, H. 4-Acetyl-2-hydroxy-2,5-dimethylfuran-3(2H)-one. Molbank 2016, 2016, M913.
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