N'-[2-(7,8-Dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)ethylidene]-4-nitrobenzohydrazide
by
Masayuki Morikawa, Katsuhito Kino *, Eriko Asada, Kosuke Katagiri, Kanami Mori-Yasumoto, Masayo Suzuki, Takanobu Kobayashi and Hiroshi Miyazawa
Masayuki Morikawa, Katsuhito Kino *, Eriko Asada, Kosuke Katagiri, Kanami Mori-Yasumoto, Masayo Suzuki, Takanobu Kobayashi and Hiroshi Miyazawa
Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University, 1314-1 Shido, Sanuki, Kagawa 769-2193, Japan
*
Author to whom correspondence should be addressed.
Molbank 2014, 2014(4), M836; https://doi.org/10.3390/M836
Received: 6 August 2014 / Accepted: 23 October 2014 / Published: 28 October 2014
The title compound, N'-[2-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin- 10(2H)-yl)ethylidene]-4-nitrobenzohydrazide (1), was obtained by the reaction of formylmethylflavin and p-nitrobenzohydrazide. The product 1 inhibited the DNA binding of nuclear factor-κB, and was characterized by 1H-NMR, 13C-NMR, electrospray ionization mass spectrometry, elemental analysis, IR and UV.
View Full-Text
Keywords:
flavin; Nuclear factor-κB; inhibitor; DNA binding
▼
Show Figures
Graphical abstract
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
- Supplementary File 1:
Supplementary (PDF, 1042 KB)
- Supplementary File 2:
molbank 3D structure (MOL, 3 KB)
Display in JSmol Viewer
3D structure generated by CORINA Classic by MN-AM. - Supplementary File 3:
molbank (INCHI, 1 KB)
- Supplementary File 4:
molbank (MOL, 3 KB)
Display in JSmol Viewer
MDPI and ACS Style
Morikawa, M.; Kino, K.; Asada, E.; Katagiri, K.; Mori-Yasumoto, K.; Suzuki, M.; Kobayashi, T.; Miyazawa, H. N'-[2-(7,8-Dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)ethylidene]-4-nitrobenzohydrazide. Molbank 2014, 2014, M836.
Show more citation formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.
