Next Article in Journal
4,5-Dimethylbenzene-1,2-dimethanol
Previous Article in Journal
N2-tert-Butoxycarbonyl-N5-[N-(9-fluorenylmethyloxycarbonyl)-2-aminoethyl]-(S)-2,5-diaminopentanoic Acid
Open AccessShort Note

(R)-(−)-2-[(5-Oxido-5-phenyl-5λ4-isoquino[4,3-c][2,1]benzothiazin-12-yl)amino]benzonitrile

Institute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, D-52074 Aachen, Germany
*
Author to whom correspondence should be addressed.
Molbank 2014, 2014(3), M834; https://doi.org/10.3390/M834
Received: 25 July 2014 / Accepted: 19 August 2014 / Published: 26 August 2014
Copper-catalyzed cross-coupling between (S)-S-methyl-S-phenylsulfoximine (1) and 2-iodobenzonitrile (2) resulted in the discovery of an unprecedented one-pot triple arylation sequence to give (R)-(−)-2-[(5-oxido-5-phenyl-5λ4-isoquino[4,3-c][2,1]benzothiazin- 12-yl)amino]benzonitrile (4). Here, we describe the synthesis of the title compound (R)-4 and the elucidation of its structure by means of various techniques. View Full-Text
Keywords: sulfoximines; benzothiazines; arylation; copper catalysis sulfoximines; benzothiazines; arylation; copper catalysis
Show Figures

Graphical abstract

MDPI and ACS Style

Frings, M.; Atodiresei, I.; Bolm, C. (R)-(−)-2-[(5-Oxido-5-phenyl-5λ4-isoquino[4,3-c][2,1]benzothiazin-12-yl)amino]benzonitrile. Molbank 2014, 2014, M834.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Only visits after 24 November 2015 are recorded.
Back to TopTop