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4-[5-(3,5-Difluorophenyl)furan-2-yl]-2,3,7-triazaspiro[4.5]dec-3-en-1-one Hydrochloride

1
Department of Studies in Chemistry, Mangalore University, Mangalagangotri-574 199, Karnataka, India
2
Aurigene Discovery Technologies Limited, Electronics city, Phase-II, Bangalore-560 100, Karnataka, India
3
Research Department of Chemistry, P. A College of Engineering, Nadupadavu, Mangalore 574153, Karnataka, India
*
Author to whom correspondence should be addressed.
Molbank 2012, 2012(3), M773; https://doi.org/10.3390/M773
Received: 3 July 2012 / Accepted: 21 August 2012 / Published: 24 August 2012
A novel route for the synthesis of new spirocyclic derivative is developed. The present work involves the synthesis of title compound 3 by Suzuki coupling of 3,5-difluorophenyl boronic acid with tert-butyl 1-(5-bromofuran-2-yl)-4-oxo-2,3,7-triazaspiro[4.5]dec-1-ene-7-carboxylate (2), which in turn prepared from the ethyl nipecotate (1). Newly prepared spirocyclic derivative (3) is characterized by IR, NMR and mass spectral data. View Full-Text
Keywords: spirocyclic; pyrazolone; Suzuki coupling; ethyl nipecotate spirocyclic; pyrazolone; Suzuki coupling; ethyl nipecotate
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MDPI and ACS Style

Srinivasan, R.; Narayana, B.; Samshuddin, S.; Sarojini, B.K. 4-[5-(3,5-Difluorophenyl)furan-2-yl]-2,3,7-triazaspiro[4.5]dec-3-en-1-one Hydrochloride. Molbank 2012, 2012, M773.

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