Extraction of Glycyrrhizic Acid and Glabridin from Licorice
Center for Advanced Bioseperation Technology, Department of Chemical Engineering, Inha University, Incheon 402-751, Korea
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Int. J. Mol. Sci. 2008, 9(4), 571-577; https://doi.org/10.3390/ijms9040571
Received: 25 January 2008
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Revised: 18 February 2008
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Accepted: 12 March 2008
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Published: 16 April 2008
(This article belongs to the Section Biochemistry)
The extraction and separation conditions of glycyrrhizic acid and glabridin from licorice were investigated. By changing the different extraction solvents, procedures, times and temperature, the optimum extraction condition was established: the used of ethanol/water (30:70, v/v) as an extraction solvent, and 60 min dipping time under 50°C. The extracts of licorice were separated and determined by reversed-phase high performance liquid chromatography with a methanol/water (70:30, v/v, containing 1% acetic acid) as the mobile phase. Under the optimum extraction condition, 2.39 mg/g of glycyrrhizic acid and 0.92 mg/g of glabridin were extracted from Chinese licorice and the recoveries were 89.7% and 72.5% respectively.
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Keywords:
glycyrrhizic acid; glabridin; licorice; extraction; high-performance liquid chromatography
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MDPI and ACS Style
Tian, M.; Yan, H.; Row, K.H. Extraction of Glycyrrhizic Acid and Glabridin from Licorice. Int. J. Mol. Sci. 2008, 9, 571-577. https://doi.org/10.3390/ijms9040571
AMA Style
Tian M, Yan H, Row KH. Extraction of Glycyrrhizic Acid and Glabridin from Licorice. International Journal of Molecular Sciences. 2008; 9(4):571-577. https://doi.org/10.3390/ijms9040571
Chicago/Turabian StyleTian, Minglei, Hongyuan Yan, and Kyung H. Row. 2008. "Extraction of Glycyrrhizic Acid and Glabridin from Licorice" International Journal of Molecular Sciences 9, no. 4: 571-577. https://doi.org/10.3390/ijms9040571
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