Next Article in Journal
Correction: Serrasqueiro et al. Targeting the Mannose Receptor with Functionalized Fucoidan/Chitosan Nanoparticles Triggers the Classical Activation of Macrophages. Int. J. Mol. Sci. 2023, 24, 9908
Previous Article in Journal
From Synaptic Plasticity to Neurotoxicity: Endocannabinoid Influence on Addiction and Neurodegeneration
Previous Article in Special Issue
Neuroprotective Effects of Low-Dose Graphenic Materials on SN4741 Embryonic Stem Cells Against ER Stress and MPTP-Induced Oxidative Stress
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
IJMS
Volume 26
Issue 23
10.3390/ijms262311633
ijms-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Review

The Effect of Silver Nanoparticle Addition on the Antimicrobial Properties of Poly(methyl methacrylate) Used for Fabrication of Dental Appliances: A Systematic Review

by
Kacper Galant
1,
Maja Podziewska
1,
Maciej Chęciński
2,3,
Kamila Chęcińska
2,
Natalia Turosz
2,3,
Dariusz Chlubek
4,*,
Tomasz Korcz
2 and
Maciej Sikora
2,3,4
1
Faculty of Medicine, Medical University of Lodz, Al. Kościuszki 4, 90-419 Łódź, Poland
2
National Medical Institute of the Ministry of the Interior and Administration, Wołoska 137, 02-507 Warsaw, Poland
3
Department of Maxillofacial Surgery, Hospital of the Ministry of Interior, Wojska Polskiego 51, 25-375 Kielce, Poland
4
Department of Biochemistry and Medical Chemistry, Pomeranian Medical University, Powstańców Wielkopolskich 72, 70-111 Szczecin, Poland
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2025, 26(23), 11633; https://doi.org/10.3390/ijms262311633
Submission received: 14 October 2025 / Revised: 18 November 2025 / Accepted: 24 November 2025 / Published: 30 November 2025
(This article belongs to the Special Issue Nanoparticles in Nanobiotechnology and Nanomedicine: 2nd Edition)
Browse Figures
Versions Notes

Abstract

Polymethyl methacrylate (PMMA) is widely used in modern dentistry, particularly in prosthodontics, orthodontics, and maxillofacial surgery. To improve the properties of PMMA, silver nanoparticles (AgNPs) are incorporated to enhance the antibacterial, antiviral, and antifungal effects of this material. This study aims to evaluate the antimicrobial properties of AgNPs as an additive to PMMA. Medical databases covered by the ACM, BASE, PubMed, and Scopus engines were searched. Of the 670 identified records, 23 studies were included that assessed the antibacterial and antifungal properties gained by incorporating AgNPs into PMMA. All of the studies included also contained a control group—PMMA without additives. Studies that evaluated nanoparticles other than AgNPs or materials other than PMMA were excluded. The data collected from the articles included the size and concentration of the nanoparticles, the method of sample preparation, sample size, information on the effect of nanoparticles on antimicrobial properties, and the contact time between the sample and the test tube containing fungi or bacteria. The data were presented in tables and graphs. The analysis indicated that increasing the weight percent concentration of AgNPs or extending the incubation time increases the antifungal efficacy. The result of Tau Kendall correlation showed that the pairs of data, concentration/incubation time and outcomes, are inversely proportional for fungi (p < 0.01). The results of the study are not entirely conclusive. Some limitations suggest the need for more standardized studies, which ideally should be conducted on human research groups and followed by a study of these properties and their effects on the human body. This systematic review followed PRISMA 2020 guidelines. The protocol was submitted to the Open Science Framework Registries (1 December 2024).
Keywords: silver nanoparticles; antimicrobial properties; poly(methyl methacrylate); PMMA; dental materials; nanotechnology silver nanoparticles; antimicrobial properties; poly(methyl methacrylate); PMMA; dental materials; nanotechnology
Graphical Abstract

Share and Cite

MDPI and ACS Style

Galant, K.; Podziewska, M.; Chęciński, M.; Chęcińska, K.; Turosz, N.; Chlubek, D.; Korcz, T.; Sikora, M. The Effect of Silver Nanoparticle Addition on the Antimicrobial Properties of Poly(methyl methacrylate) Used for Fabrication of Dental Appliances: A Systematic Review. Int. J. Mol. Sci. 2025, 26, 11633. https://doi.org/10.3390/ijms262311633

AMA Style

Galant K, Podziewska M, Chęciński M, Chęcińska K, Turosz N, Chlubek D, Korcz T, Sikora M. The Effect of Silver Nanoparticle Addition on the Antimicrobial Properties of Poly(methyl methacrylate) Used for Fabrication of Dental Appliances: A Systematic Review. International Journal of Molecular Sciences. 2025; 26(23):11633. https://doi.org/10.3390/ijms262311633

Chicago/Turabian Style

Galant, Kacper, Maja Podziewska, Maciej Chęciński, Kamila Chęcińska, Natalia Turosz, Dariusz Chlubek, Tomasz Korcz, and Maciej Sikora. 2025. "The Effect of Silver Nanoparticle Addition on the Antimicrobial Properties of Poly(methyl methacrylate) Used for Fabrication of Dental Appliances: A Systematic Review" International Journal of Molecular Sciences 26, no. 23: 11633. https://doi.org/10.3390/ijms262311633

APA Style

Galant, K., Podziewska, M., Chęciński, M., Chęcińska, K., Turosz, N., Chlubek, D., Korcz, T., & Sikora, M. (2025). The Effect of Silver Nanoparticle Addition on the Antimicrobial Properties of Poly(methyl methacrylate) Used for Fabrication of Dental Appliances: A Systematic Review. International Journal of Molecular Sciences, 26(23), 11633. https://doi.org/10.3390/ijms262311633

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop