Advances in Bioactive Compounds and Cancer Therapy—Insights from the Special Issue “Bioactive Compounds in Cancers”
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
List of Contributions
- Gnanamony, M.; Thomas, M.; Nguyen, T.H.; Brownstein, K.; de Alarcon, P.A. Pomiferin Induces Antiproliferative and Pro-Death Effects in High-Risk Neuroblastoma Cells by Modulating Multiple Cell Death Pathways. Int. J. Mol. Sci. 2025, 26, 3600.
- Reyes, C.P.; Ardiles, A.; Anaissi-Afonso, L.; González-Bakker, A.; Padrón, J.M.; Jiménez, I.A.; Machín, F.; Bazzocchi, I.L. Exploring the Anticancer Potential of Phenolic nor-Triterpenes from Celastraceae Species. Int. J. Mol. Sci. 2024, 25, 9470.
- Szczepański, J.; Khylyuk, D.; Korga-Plewko, A.; Michalczuk, M.; Mańdziuk, S.; Iwan, M.; Trotsko, N. Rhodanine–Piperazine Hybrids as Potential VEGFR, EGFR, and HER2 Targeting Anti-Breast Cancer Agents. Int. J. Mol. Sci. 2024, 25, 12401.
- Maldonado, J.; Oliva, A.; Guzmán, L.; Molinari, A.; Acevedo, W. Synthesis, Anticancer Activity, and Docking Studies of Novel Hydroquinone-Chalcone-Pyrazoline Hybrid Derivatives. Int. J. Mol. Sci. 2024, 25, 7281.
- Barbosa, F.; Araújo, J.; Gonçalves, V.M.F.; Palmeira, A.; Cunha, A.; Silva, P.M.A.; Fernandes, C.; Pinto, M.; Bousbaa, H.; Queirós, O.; et al. Evaluation of Antitumor Activity of Xanthones Conjugated with Amino Acids. Int. J. Mol. Sci. 2024, 25, 2121.
- Moreira, J.; Silva, P.M.A.; Castro, E.; Saraiva, L.; Pinto, M.; Bousbaa, H.; Cidade, H. BP-M345 as a Basis for the Discovery of New Diarylpentanoids with Promising Antimitotic Activity. Int. J. Mol. Sci. 2024, 25, 1691.
- Kot, Y.; Klochkov, V.; Prokopiuk, V.; Sedyh, O.; Tryfonyuk, L.; Grygorova, G.; Karpenko, N.; Tomchuk, O.; Kot, K.; Onishchenko, A.; et al. GdVO4:Eu3+ and LaVO4:Eu3+ Nanoparticles Exacerbate Oxidative Stress in L929 Cells: Potential Implications for Cancer Therapy. Int. J. Mol. Sci. 2024, 25, 11687.
- Duda-Madej, A.; Viscardi, S.; Szewczyk, W.; Topola, E. Natural Alkaloids in Cancer Therapy: Berberine, Sanguinarine and Chelerythrine against Colorectal and Gastric Cancer. Int. J. Mol. Sci. 2024, 25, 8375.
References
- International Agency for Research on Cancer. Cancer Tomorrow: Estimating the Future Burden of Cancer. Lyon, France: IARC. 2024. Available online: https://gco.iarc.fr/tomorrow (accessed on 4 June 2025).
- Bhat, G.R.; Sethi, I.; Sadida, H.Q.; Rah, B.; Mir, R.; Algehainy, N.; Albalawi, I.A.; Masoodi, T.; Subbaraj, G.K.; Jamal, F.; et al. Cancer Cell Plasticity: From Cellular, Molecular, and Genetic Mechanisms to Tumor Heterogeneity and Drug Resistance. Cancer Metastasis Rev. 2024, 43, 197–228. [Google Scholar] [CrossRef] [PubMed]
- Gu, Y.; Yang, R.; Zhang, Y.; Guo, M.; Takehiro, K.; Zhan, M.; Yang, L.; Wang, H. Molecular Mechanisms and Therapeutic Strategies in Overcoming Chemotherapy Resistance in Cancer. Mol. Biomed. 2025, 6, 2. [Google Scholar] [CrossRef] [PubMed]
- Crucitta, S.; Cucchiara, F.; Mathijssen, R.; Mateo, J.; Jager, A.; Joosse, A.; Passaro, A.; Attili, I.; Petrini, I.; van Schaik, R.; et al. Treatment-Driven Tumour Heterogeneity and Drug Resistance: Lessons from Solid Tumours. Cancer Treat. Rev. 2022, 104, 102340. [Google Scholar] [CrossRef] [PubMed]
- Zhang, L.; Song, J.; Kong, L.; Yuan, T.; Li, W.; Zhang, W.; Hou, B.; Lu, Y.; Du, G. The Strategies and Techniques of Drug Discovery from Natural Products. Pharmacol. Ther. 2020, 216, 107686. [Google Scholar] [CrossRef] [PubMed]
- Zou, J.Y.; Chen, Q.L.; Luo, X.C.; Damdinjav, D.; Abdelmohsen, U.R.; Li, H.Y.; Battulga, T.; Chen, H.B.; Wang, Y.Q.; Zhang, J.Y. Natural Products Reverse Cancer Multidrug Resistance. Front. Pharmacol. 2024, 15, 1348076. [Google Scholar] [CrossRef] [PubMed]
Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content. |
© 2025 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Share and Cite
Bousbaa, H.; Cidade, H.; Silva, P.M.A. Advances in Bioactive Compounds and Cancer Therapy—Insights from the Special Issue “Bioactive Compounds in Cancers”. Int. J. Mol. Sci. 2025, 26, 5632. https://doi.org/10.3390/ijms26125632
Bousbaa H, Cidade H, Silva PMA. Advances in Bioactive Compounds and Cancer Therapy—Insights from the Special Issue “Bioactive Compounds in Cancers”. International Journal of Molecular Sciences. 2025; 26(12):5632. https://doi.org/10.3390/ijms26125632
Chicago/Turabian StyleBousbaa, Hassan, Honorina Cidade, and Patrícia M. A. Silva. 2025. "Advances in Bioactive Compounds and Cancer Therapy—Insights from the Special Issue “Bioactive Compounds in Cancers”" International Journal of Molecular Sciences 26, no. 12: 5632. https://doi.org/10.3390/ijms26125632
APA StyleBousbaa, H., Cidade, H., & Silva, P. M. A. (2025). Advances in Bioactive Compounds and Cancer Therapy—Insights from the Special Issue “Bioactive Compounds in Cancers”. International Journal of Molecular Sciences, 26(12), 5632. https://doi.org/10.3390/ijms26125632