RETRACTED: Gu et al. Long Coding RNA XIST Contributes to Neuronal Apoptosis through the Downregulation of AKT Phosphorylation and Is Negatively Regulated by miR-494 in Rat Spinal Cord Injury. Int. J. Mol. Sci. 2017, 18, 732

Gu, Shixin; Xie, Rong; Liu, Xiaodong; Shou, Jiajun; Gu, Wentao; Che, Xiaoming

doi:10.3390/ijms26010347

Open AccessRetraction

RETRACTED: Gu et al. Long Coding RNA XIST Contributes to Neuronal Apoptosis through the Downregulation of AKT Phosphorylation and Is Negatively Regulated by miR-494 in Rat Spinal Cord Injury. Int. J. Mol. Sci. 2017, 18, 732

by

Shixin Gu

^†,

Rong Xie

^†,

Xiaodong Liu

,

Jiajun Shou

,

Wentao Gu

and

Xiaoming Che

^*

Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai 200040, China

^*

Author to whom correspondence should be addressed.

^†

The authors contributed equally to this work.

Int. J. Mol. Sci. 2025, 26(1), 347; https://doi.org/10.3390/ijms26010347

Submission received: 12 October 2024 / Accepted: 4 December 2024 / Published: 3 January 2025

(This article belongs to the Section Molecular Biology)

Download Versions Notes

The journal retracts the article titled “Long Coding RNA XIST Contributes to Neuronal Apoptosis through the Downregulation of AKT Phosphorylation and Is Negatively Regulated by miR-494 in Rat Spinal Cord Injury” [1], cited above.

Following publication, concerns were brought to the attention of the Editorial Office regarding image duplication between this article [1], and an earlier publication [2], produced by a different authorship group.

Adhering to our standard procedure, the Editorial Office and Editorial Board conducted an investigation that confirmed the overlap between Figure 4A (AKT band) [1], and Figure 4F (β-actin band) [2]. While the authors collaborated within the investigation, they were unable to satisfactorily explain the overlap or provide raw material for Editorial Board evaluation. Consequently, the Editorial Board has lost confidence in the reliability of the findings and decided to retract this publication [1], as per MDPI’s retraction policy (https://www.mdpi.com/ethics#_bookmark30).

This retraction was approved by the Editor-in Chief of the International Journal of Molecular Sciences journal.

The authors did not agree with this retraction.

References

Gu, S.; Xie, R.; Liu, X.; Shou, J.; Gu, W.; Che, X. RETRACTED: Long Coding RNA XIST Contributes to Neuronal Apoptosis through the Downregulation of AKT Phosphorylation and Is Negatively Regulated by miR-494 in Rat Spinal Cord Injury. Int. J. Mol. Sci. 2017, 18, 732. [Google Scholar] [CrossRef] [PubMed]
Wang, Y.; Xu, S.; Wu, Y.; Zhang, J. Cucurbitacin E inhibits osteosarcoma cells proliferation and invasion through attenuation of PI3K/AKT/mTOR signalling pathway. Biosci. Rep. 2016, 36, e00405. [Google Scholar] [CrossRef] [PubMed]

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© 2025 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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MDPI and ACS Style

Gu, S.; Xie, R.; Liu, X.; Shou, J.; Gu, W.; Che, X. RETRACTED: Gu et al. Long Coding RNA XIST Contributes to Neuronal Apoptosis through the Downregulation of AKT Phosphorylation and Is Negatively Regulated by miR-494 in Rat Spinal Cord Injury. Int. J. Mol. Sci. 2017, 18, 732. Int. J. Mol. Sci. 2025, 26, 347. https://doi.org/10.3390/ijms26010347

AMA Style

Gu S, Xie R, Liu X, Shou J, Gu W, Che X. RETRACTED: Gu et al. Long Coding RNA XIST Contributes to Neuronal Apoptosis through the Downregulation of AKT Phosphorylation and Is Negatively Regulated by miR-494 in Rat Spinal Cord Injury. Int. J. Mol. Sci. 2017, 18, 732. International Journal of Molecular Sciences. 2025; 26(1):347. https://doi.org/10.3390/ijms26010347

Chicago/Turabian Style

Gu, Shixin, Rong Xie, Xiaodong Liu, Jiajun Shou, Wentao Gu, and Xiaoming Che. 2025. "RETRACTED: Gu et al. Long Coding RNA XIST Contributes to Neuronal Apoptosis through the Downregulation of AKT Phosphorylation and Is Negatively Regulated by miR-494 in Rat Spinal Cord Injury. Int. J. Mol. Sci. 2017, 18, 732" International Journal of Molecular Sciences 26, no. 1: 347. https://doi.org/10.3390/ijms26010347

APA Style

Gu, S., Xie, R., Liu, X., Shou, J., Gu, W., & Che, X. (2025). RETRACTED: Gu et al. Long Coding RNA XIST Contributes to Neuronal Apoptosis through the Downregulation of AKT Phosphorylation and Is Negatively Regulated by miR-494 in Rat Spinal Cord Injury. Int. J. Mol. Sci. 2017, 18, 732. International Journal of Molecular Sciences, 26(1), 347. https://doi.org/10.3390/ijms26010347

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

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RETRACTED: Gu et al. Long Coding RNA XIST Contributes to Neuronal Apoptosis through the Downregulation of AKT Phosphorylation and Is Negatively Regulated by miR-494 in Rat Spinal Cord Injury. Int. J. Mol. Sci. 2017, 18, 732

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