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Article
Peer-Review Record

Integrated Discriminant Evaluation of Molecular Genetic Markers and Genetic Diversity Parameters of Endangered Balearic Dog Breeds

Int. J. Mol. Sci. 2024, 25(5), 2706; https://doi.org/10.3390/ijms25052706
by José Manuel Alanzor Puente 1, Águeda Laura Pons Barro 1, Antonio González Ariza 2, María del Amparo Martínez Martínez 3, Juan Vicente Delgado Bermejo 3 and Francisco Javier Navas González 3,*
Reviewer 1:
Reviewer 2: Anonymous
Int. J. Mol. Sci. 2024, 25(5), 2706; https://doi.org/10.3390/ijms25052706
Submission received: 27 January 2024 / Revised: 15 February 2024 / Accepted: 22 February 2024 / Published: 26 February 2024

Round 1

Reviewer 1 Report

Comments and Suggestions for Authors

The research is devoted to the important problem of the biodiversity conservation of domestic animals, in particular, unique local breeds of dogs. To develop conservation programs, it is necessary to understand the genetic structure of existing populations, the degree of inbreeding in them, and the identification of specific genetic markers. The authors have carried out a large amount of genetic research on endangered Balearic dog breeds using modern methods. The results are presented and analyzed in detail. As a note:

1. The Abstract must reflect the content of the article, including the results of the study.This section should be supplemented with the obtained digital data. This edition does not show the large volume of interesting research carried out. 

2. In Discussion section, your should discuss your own experimental data in comparison with the data of other researches. In this article, the Discussion includes a large amount of information (lines 419-496), which, in my opinion, should be moved to the Introduction section. 

3. The Conclusion section in this article contains mainly general considerations, but 6 dog breeds were studied, each of which has its own specific characteristics. The conclusions should be specified so that the research results can be  used by breeders working with a particular breed.

4. In Figure 4,  the Y axis should be labeled in English.

Author Response

Reviewer: 1


The research is devoted to the important problem of the biodiversity conservation of domestic animals, in particular, unique local breeds of dogs. To develop conservation programs, it is necessary to understand the genetic structure of existing populations, the degree of inbreeding in them, and the identification of specific genetic markers. The authors have carried out a large amount of genetic research on endangered Balearic dog breeds using modern methods. The results are presented and analyzed in detail.

 

 

Response: We thank the reviewer for his/her kind comments.

 

As a note:

  1. The Abstract must reflect the content of the article, including the results of the study.This section should be supplemented with the obtained digital data. This edition does not show the large volume of interesting research carried out. 

 

Response: We followed the reviewer suggestion.

 

  1. In Discussion section, your should discuss your own experimental data in comparison with the data of other researches. In this article, the Discussion includes a large amount of information (lines 419-496), which, in my opinion, should be moved to the Introduction section. 

 

Response: We understand the reviewer comment as in the manner the paragraph was introducted, it seemed to be aprt of the introduction. However, these are the results and explanations for multicollinearity analyses. We clarified this in the body text in order to make it fit the style in which discussion should eb written.

 

  1. The Conclusion section in this article contains mainly general considerations, but 6 dog breeds were studied, each of which has its own specific characteristics. The conclusions should be specified so that the research results can be  used by breeders working with a particular breed.

 

Response: Reviewer suggestion was followed.

 

 

  1. In Figure 4,  the Y axis should be labeled in English.

 

Response: Reviewer suggestion was followed.

 

Reviewer 2 Report

Comments and Suggestions for Authors

Manuscript entitled “Integrated Discriminant Evaluation of Molecular Genetic Markers and Genetic Diversity Parameters of Endangered Balearic Dog Breeds” studies six endangered dog breeds present in the Balearic Islands, through the use of microsatellite markers 

The manuscript is well structured and well written and deserves to be published on IJMS.

The text is very extensive, especially the discussion section; it could be reduced, as well as the results section could be reduced with the use of tables.

The authors should state in their manuscript that microsatellite analysis is not the most up-to-date method for analyzing and comparing the dog genome. 

Minor suggestions

please add some pictures of the dog breeds analyzed

 

please indicate the version, each time you use a software tool

 

please write the dog species in italics

 

Author Response

 

Reviewer 2.

 

Manuscript entitled “Integrated Discriminant Evaluation of Molecular Genetic Markers and Genetic Diversity Parameters of Endangered Balearic Dog Breeds” studies six endangered dog breeds present in the Balearic Islands, through the use of microsatellite markers 

The manuscript is well structured and well written and deserves to be published on IJMS.

 

Response: We thank the reviewer for his/her kind comments.

 

The text is very extensive, especially the discussion section; it could be reduced, as well as the results section could be reduced with the use of tables.

 

Response: We reduced the discussion section 4304 words to 2691 words.

 

The authors should state in their manuscript that microsatellite analysis is not the most up-to-date method for analyzing and comparing the dog genome. 

 

Response: We followed reviewer suggestion.

 

Minor suggestions

please add some pictures of the dog breeds analyzed

 

Response: Figure 5 was added.

 

please indicate the version, each time you use a software tool

 

Response: We followed the reviewer suggestion.

 

please write the dog species in italics

 

Response: We followed the reviewer suggestion.

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