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Volume 24
Issue 8
10.3390/ijms24087004
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Article
Peer-Review Record

Preliminary Approaches to Cosmeceuticals Emulsions Based on N-ProlylPalmitoyl Tripeptide-56 Acetat-Bakuchiol Complex Intended to Combat Skin Oxidative Stress

Int. J. Mol. Sci. 2023, 24(8), 7004; https://doi.org/10.3390/ijms24087004
by Ana Simona Barna 1, Claudia Maxim 1,*, Adriana Trifan 2, Alexandra Cristina Blaga 1, Ramona Cimpoesu 3, Delia Turcov 1 and Daniela Suteu 1,*
Reviewer 1: Anonymous
Reviewer 2: Anonymous
Int. J. Mol. Sci. 2023, 24(8), 7004; https://doi.org/10.3390/ijms24087004
Submission received: 20 March 2023 / Revised: 6 April 2023 / Accepted: 7 April 2023 / Published: 10 April 2023
(This article belongs to the Special Issue Bioactive Molecules of Natural Origin: Mechanisms of Action Related to Health Risks and Benefits 2.0)

Round 1

Reviewer 1 Report

I recommend the manuscript titled "Preliminary approaches about cosmeceuticals emulsions based on N-ProlylPalmitoyl Tripeptide-56 Acetat - Bakuchiol complex intended to combat skin oxidative stress"  to be accepted after revision done. Therefore, I propose:

1. Introduction:

- Is there a concern that dermo-cosmetics have a shorter shelf life? Or do they deteriorate faster? There is no information about the stability of these preparations and the possibility of using them after opening the cosmetics.

- page 2, lines 96-97: is there a risk of cancer when improving the potential of cosmetics with increase cell production substances?

- page 2, line 95: thanks is used in the wrong context, it should be through.

2. Methods:

- page 4, line 155 abbreviation HLB what is it? There is no explanation.

- Figure 2, tables 2, 3, 4, 5 - no explanation what is E1, E1.1, etc.

3. Results and discussion: No discussion or commentary of centrifugation test, vibration test, antioxidant activity results. Especially increase of antioxidant activity is worth a broader discussion and discussion.

Author Response

Please see the attachment.

Author Response File: Author Response.pdf

Reviewer 2 Report

The manuscript systematically evaluated the emulsions of BAK-TPA complexes. It is well-organized and well-written and of interest to the journal's audiences. I would recommend accepting it after the minor corrections are addressed. 

L18: "emulsions"

L150: The structure in Figure 1 has to be redrawn. 

L173: "15 rpm"

L322:Please reorganize this sentence.

L363: Please rewrite the sentence "The effects will ...)

L405: " would be assured..."

L488: "The determinations..."

L499: " 1mm2" has to be corrected

L475: "TPC ug/5 mL (   )" has to be double checked

Reference session: please keep the citations' format consistent as the journal requested. Please check it throughout the whole session.

 

 

Author Response

Please see the attachment.

Author Response File: Author Response.pdf

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