Xylanase Inhibitors: Defense Players in Plant Immunity with Implications in Agro-Industrial Processing
Abstract
:1. Introduction
2. XIs Genomic Organization
3. Inhibition Activity of XIs
4. Structural Properties of Xylanase-XI Interaction
5. XI Regulation and Localization
6. Role of XIs in Plant Defense and Crop Engineering for Plant Protection
7. Strategies to Reduce the Effect of XIs in Food Processing and Quality
Strategy | References |
---|---|
Heat treatment of matrices containing XIs | [105] |
Selection of plant row materials with low xylanase inhibitory activity | [106] |
Application of xylanases that escape the inhibition of xylanase inhibitors | [64] |
Engineering xylanases that escape the inhibition of xylanase inhibitors and/or with improved catalytic activity and thermostability | [60,92,107,112,113,114] |
Adjustment of xylanase dosage | [115,116] |
Targeted disruption of specific XIs in plant species used in agro-industrial processes | [42] |
8. Involvement of XIs in Food Allergy
9. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Xylanase | GH | Origin | TAXI-I | TAXI-II | TAXI-III | TAXI-IV | XIP-I | TLXI | RIXI | riceXIP | OsXIP | OsHI-XIP | XAIP | References |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aspergillus aculeatus (AaXyl2) | 10 | F | no | no | no | no | [31,44,49,53] | |||||||
Aspergillus fumigatus xylanase A (AfXylA10) | 10 | F | 177.94 | [54] | ||||||||||
Aspergillus nidulans (AnidXlnC) | 10 | F | no | no | 9 | [44,49,53] | ||||||||
Aspergillus niger (XynIII) | 11 | F | yes | [41] | ||||||||||
Aspergillus niger (AnExlA/AnxA/ANX) | 11 | F | 20.1 | no | 317 | 135 | yes | yes | [31,44,49,53,55,56,57,58,59,60,61] | |||||
Aspergillus niger hybrid mutant of AnxA xylanase and TfxA_CD (FSI-124) | 11 | F/B | yes | [60] | ||||||||||
Aspergillus niger (AnM4Xyl) | 11 | F | 18.8 | [21] | ||||||||||
Aspergillus niger (AnXynA) | 10 | F | no | no | yes | no | yes | [31,49,53,59] | ||||||
Aspergillus niger (Xyn10) | 10 | F | yes | [41] | ||||||||||
Aspergillus niger xylanase hybrid of AnxA xylanase and TfxA_CD (Atx) | 11 | F/B | yes | [55,60] | ||||||||||
Aspergillus oryzae (AoXyn) | 10 | F | no | no | 17 | no | [31,44,53] | |||||||
Bacillus agaradhaerens (BaXyl) | 11 | B | no | [44] | ||||||||||
Bacillus amyloliquefaciens (reBaxA) | 11 | B | yes | yes | 54.09 | [55,57,60,62] | ||||||||
Bacillus amyloliquefaciens xylanase mutant of reBaxA (reBaxA454) | 11 | B | yes | [57] | ||||||||||
Bacillus amyloliquefaciens xylanase mutant of reBaxA (reBaxA50) | 11 | B | yes | [55,60] | ||||||||||
Bacillus amyloliquefaciens xylanase mutant T331 of reBaxA (DS199) | 11 | B | 12.16 | [62] | ||||||||||
Bacillus sp. | 10 | B | no | [44] | ||||||||||
Bacillus subtilis (BsXynA) | 11 | B | 16.7 | yes | no | no | [31,44,49,53,56] | |||||||
Bacillus subtilis (BSX) | 11 | B | yes | yes | yes | [59,61] | ||||||||
Botrytis cinerea (BcXyn11a) | 11 | F | 6 | no | 2.1 | [63] | ||||||||
Chrysosporium lucknowense (ClXynB) | 10 | F | no | no | no | [64] | ||||||||
Chrysosporium lucknowense (ClXynC) | 10 | F | no | no | no | [64] | ||||||||
Fibrobacter succinogenes (FsXynC) | 11 | B | no | [44,53] | ||||||||||
Flavobacterium sp. MSY-2 (rXFH) | 10 | B | no | no | [65] | |||||||||
Fusarium graminearum (FCSG_11487) | 10 | F | no | no | no | no | no | no | [39,66,67] | |||||
Fusarium graminearum (FGSG_03624) | 11 | F | yes | yes | 2.59 | yes | no | no | [21,39,66,67,68] | |||||
Fusarium graminearum (FGSG_10999) | 11 | F | yes | yes | 12.04 | yes | no | no | [39,66,67,68] | |||||
Fusarium graminearum (FGSG_11304) | 10 | F | no | no | no | no | 83.7 | no | [39,66,67] | |||||
Hu sheep rumen microbiota (XYN-LXY_CD, catalytic domain) | 10 | B | 237.37 | [69] | ||||||||||
Hypothenemus hampei (HhXyl) | 10 | I | yes | [70] | ||||||||||
Neocallimastix patriciarum (NpXynA) | 11 | F | no | no | [71,72] | |||||||||
Neocallimastix sp. GMLF1 (Xyn1B) | 11 | F | no | [71] | ||||||||||
Oryza sativa (OSX) | 10 | P | no | [59] | ||||||||||
Paenibacillus sp | U | B | yes | [41] | ||||||||||
Penicillium funiculosum (not specified) | 11 | F | yes | [73] | ||||||||||
Penicillium funiculosum (PfXynA) | 7 | F | 46 | 46 | 106 | [74] | ||||||||
Penicillium funiculosum (PfXynB) | 11 | F | 2.9 | no | 89.7 | [75,76] | ||||||||
Penicillium funiculosum (PfXynC) | 11 | F | 16 | 17 | 3.4 | 289.6 | [31,44,49,75,77,78] | |||||||
Penicillium funiculosum (PfXynD) | 10 | F | no | no | yes | [74] | ||||||||
Penicillium griseofulvum (PgXynA) | 11 | F | no | [77] | ||||||||||
Penicillium occitanis Pol6 (PoXyn3) | 11 | F | yes | [78] | ||||||||||
Penicillium purpurogenum (PpXynA) | 10 | F | no | no | no | [31,49,53] | ||||||||
Penicillium purpurogenum (PpXynB) | 11 | F | yes | yes | [49,53,75] | |||||||||
Pseudoalteromonas haloplanktis TAH3A (XPH) | 8 | B | no | no | no | no | [65] | |||||||
Pseudomonas fluorescens (PfXynA) | 10 | B | no | no | [31,44] | |||||||||
Talaromyces emersonii xylanase (TeX-1) | 10 | F | no | no | [49] | |||||||||
Thermobacillus xylanilyticus (TxXyl) | 11 | B | 234.7 | [31] | ||||||||||
Thermobacillus xylanilyticus (TxXynA) | 10 | B | no | [31] | ||||||||||
Thermomonospora fusca (TFX) | 11 | B | no | [59] | ||||||||||
Thermomonospora fusca TF xylanase A catalytic domain (TfxA_CD) | 11 | B | yes | yes | [55,57] | |||||||||
Thermomonospora fusca catalytic domain TfxA_CD mutant (TfxA_CD214) | 11 | B | yes | 12.2 | [55,57,79] | |||||||||
Thermomonospora fusca catalytic domain TfxA_CD mutant (TfxA_CD309) | 11 | B | yes | yes | [55,57] | |||||||||
Thermomonospora fusca catalytic domain TfxA_CD mutant (TfxA_CD311) | 11 | B | yes | yes | [55,57] | |||||||||
Thermomonospora fusca catalytic domain TfxA_CD mutant (TfxA_CD467) | 11 | B | yes | [57] | ||||||||||
Thermomonospora fusca catalytic domain TfxA_CD mutant (TfxA_CD526) | 11 | B | yes | [57] | ||||||||||
Thermomonospora lanuginosus (TLx) | 11 | F | yes | yes | yes | yes | [20,55,57,60,79] | |||||||
Trichoderma harzianum (ThXyn1) | 11 | F | yes | [41,71] | ||||||||||
Trichoderma longibrachiatum (endo-1,4-β; M3) | 11 | F | yes | yes | yes | [20,60,79] | ||||||||
Trichoderma longibrachiatum (Xyn I) | 11 | F | 4.2 | [31] | ||||||||||
Trichoderma longibrachiatum (Xyn II) | 11 | F | no | [31] | ||||||||||
Trichoderma reesei (TRx) | 11 | F | yes | yes | [55,57] | |||||||||
Trichoderma reesei (Xyn1) | 11 | F | yes | yes | [75] | |||||||||
Trichoderma reesei (Xyn2) | 11 | F | yes | yes | [75] | |||||||||
Trichoderma viride (TvXyl) | 11 | F | yes | yes | 610 | 170.4 | [31,44,49,53,75] | |||||||
Triticum aestivum xylanase (from flour) | 10 | P | no | no | [49,51] | |||||||||
Uncultured bacterium (rXyn8) | 8 | B | no | no | no | no | [65] |
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Tundo, S.; Mandalà, G.; Sella, L.; Favaron, F.; Bedre, R.; Kalunke, R.M. Xylanase Inhibitors: Defense Players in Plant Immunity with Implications in Agro-Industrial Processing. Int. J. Mol. Sci. 2022, 23, 14994. https://doi.org/10.3390/ijms232314994
Tundo S, Mandalà G, Sella L, Favaron F, Bedre R, Kalunke RM. Xylanase Inhibitors: Defense Players in Plant Immunity with Implications in Agro-Industrial Processing. International Journal of Molecular Sciences. 2022; 23(23):14994. https://doi.org/10.3390/ijms232314994
Chicago/Turabian StyleTundo, Silvio, Giulia Mandalà, Luca Sella, Francesco Favaron, Renesh Bedre, and Raviraj M. Kalunke. 2022. "Xylanase Inhibitors: Defense Players in Plant Immunity with Implications in Agro-Industrial Processing" International Journal of Molecular Sciences 23, no. 23: 14994. https://doi.org/10.3390/ijms232314994