Solvent-Free Formation of Cyclodextrin-Based Pseudopolyrotaxanes of Polyethylene Glycol: Kinetic and Structural Aspects
Abstract
:1. Introduction
2. Results and Discussion
2.1. Mechanism of the PPR Formation
2.1.1. Threading Step (Formation of the PPR)
2.1.2. Crystallization Step (Formation of Crystalline PPR)
2.2. PPR Structure and Stability
2.3. Effects of the Polymer Chain Length and Structure
3. Materials and Methods
3.1. Chemicals
3.2. Preparation of the Pseudopolyrotaxanes
3.3. FTIR-ATR Characterization and Kinetics
3.4. XRD Characterization
3.5. Derivative Thermogravimetric Analysis
3.6. Scanning Electron Microscopy
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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T (°C) | kth (min−1) | ||
---|---|---|---|
1:0.5 | 1:1 | 1:2 | |
25 | (3.3 ± 0.2) × 10−3 | (3.9 ± 0.3) × 10−3 | (4.7 ± 0.4) × 10−3 |
35 | (5.4 ± 0.2) × 10−3 | (5.2 ± 0.3) × 10−3 | (5.2 ± 0.4) × 10−3 |
45 | (9.4 ± 0.3) × 10−3 | (9.8 ± 0.4) × 10−3 | (8.5 ± 0.5) × 10−3 |
55 | (12.1 ± 0.8) × 10−3 | (14 ± 1) × 10−3 | (9.6 ± 0.6) × 10−3 |
65 | (28 ± 2) × 10−3 | (17 ± 1) × 10−3 | (13.9 ± 0.9) × 10−3 |
Ea (kJ mol−1) | 42 ± 4 | 34 ± 4 | 23 ± 3 |
Molar Ratio | 2θ | kc (min−1) | |
---|---|---|---|
50 °C | 75 °C | ||
1:0.5 | 19.9° | (23 ± 7) × 10−3 | (10 ± 2) × 10−3 |
1:1 | 19.9° | (26 ± 2) × 10−3 | (9 ± 3) × 10−3 |
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Guembe-Michel, N.; Durán, A.; Sirera, R.; González-Gaitano, G. Solvent-Free Formation of Cyclodextrin-Based Pseudopolyrotaxanes of Polyethylene Glycol: Kinetic and Structural Aspects. Int. J. Mol. Sci. 2022, 23, 685. https://doi.org/10.3390/ijms23020685
Guembe-Michel N, Durán A, Sirera R, González-Gaitano G. Solvent-Free Formation of Cyclodextrin-Based Pseudopolyrotaxanes of Polyethylene Glycol: Kinetic and Structural Aspects. International Journal of Molecular Sciences. 2022; 23(2):685. https://doi.org/10.3390/ijms23020685
Chicago/Turabian StyleGuembe-Michel, Nerea, Adrián Durán, Rafael Sirera, and Gustavo González-Gaitano. 2022. "Solvent-Free Formation of Cyclodextrin-Based Pseudopolyrotaxanes of Polyethylene Glycol: Kinetic and Structural Aspects" International Journal of Molecular Sciences 23, no. 2: 685. https://doi.org/10.3390/ijms23020685