A Curcumin-BODIPY Dyad and Its Silica Hybrid as NIR Bioimaging Probes
Abstract
:1. Introduction
2. Results and Discussion
2.1. Synthesis of Dyad CB-Green
2.2. Photochemical Characterization of Dyad CB-Green
2.3. Synthesis of Dye-Loaded Silica Nanoparticles
2.4. Photochemical Characterization of the Dye-Loaded Silica Nanoparticles
2.5. Biocompatibility and Cellular Uptake Evaluations
3. Material and Methods
3.1. Chemicals
3.2. Instrumentation
3.3. Synthesis
3.4. Cell Culture and Cell Viability Assay
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Compound | Absorption | Emission | ||
---|---|---|---|---|
λmax, nm (ε, M−1 cm−1) | λmax, nm | τ, ns | Φ | |
CB-Green | 705 (95,000) | 770 | 2.2 | 0.18 |
Curc | 418 (52,900) | 520 | 0.66 | 0.1 |
4 | 423 (116,100) 705 (94,800) | 770 | 2.2 | 0.2 |
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Gangemi, C.M.A.; Salerno, T.M.G.; Barattucci, A.; Cucinotta, F.; Bonaccorsi, P.; Calabrese, G.; Poma, P.; Rizzo, M.G.; Campagna, S.; Puntoriero, F. A Curcumin-BODIPY Dyad and Its Silica Hybrid as NIR Bioimaging Probes. Int. J. Mol. Sci. 2022, 23, 9542. https://doi.org/10.3390/ijms23179542
Gangemi CMA, Salerno TMG, Barattucci A, Cucinotta F, Bonaccorsi P, Calabrese G, Poma P, Rizzo MG, Campagna S, Puntoriero F. A Curcumin-BODIPY Dyad and Its Silica Hybrid as NIR Bioimaging Probes. International Journal of Molecular Sciences. 2022; 23(17):9542. https://doi.org/10.3390/ijms23179542
Chicago/Turabian StyleGangemi, Chiara Maria Antonietta, Tania Maria Grazia Salerno, Anna Barattucci, Fabio Cucinotta, Paola Bonaccorsi, Giovanna Calabrese, Paola Poma, Maria Giovanna Rizzo, Sebastiano Campagna, and Fausto Puntoriero. 2022. "A Curcumin-BODIPY Dyad and Its Silica Hybrid as NIR Bioimaging Probes" International Journal of Molecular Sciences 23, no. 17: 9542. https://doi.org/10.3390/ijms23179542