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Review

Inorganic Nanoparticles and Composite Films for Antimicrobial Therapies

1
Department of Science and Engineering of Oxide Materials and Nanomaterials, University Politehnica of Bucharest, 011061 Bucharest, Romania
2
Research Institute of the University of Bucharest—ICUB, University of Bucharest, 050657 Bucharest, Romania
*
Author to whom correspondence should be addressed.
Academic Editor: Claudio O. Gualerzi
Int. J. Mol. Sci. 2021, 22(9), 4595; https://doi.org/10.3390/ijms22094595
Received: 14 April 2021 / Revised: 23 April 2021 / Accepted: 26 April 2021 / Published: 27 April 2021
(This article belongs to the Special Issue Interactions of Nanoparticles with Biomolecules)
The development of drug-resistant microorganisms has become a critical issue for modern medicine and drug discovery and development with severe socio-economic and ecological implications. Since standard and conventional treatment options are generally inefficient, leading to infection persistence and spreading, novel strategies are fundamentally necessary in order to avoid serious global health problems. In this regard, both metal and metal oxide nanoparticles (NPs) demonstrated increased effectiveness as nanobiocides due to intrinsic antimicrobial properties and as nanocarriers for antimicrobial drugs. Among them, gold, silver, copper, zinc oxide, titanium oxide, magnesium oxide, and iron oxide NPs are the most preferred, owing to their proven antimicrobial mechanisms and bio/cytocompatibility. Furthermore, inorganic NPs can be incorporated or attached to organic/inorganic films, thus broadening their application within implant or catheter coatings and wound dressings. In this context, this paper aims to provide an up-to-date overview of the most recent studies investigating inorganic NPs and their integration into composite films designed for antimicrobial therapies. View Full-Text
Keywords: inorganic nanoparticles; antimicrobial therapy; nanobiocides; gold nanoparticles; silver nanoparticles; copper nanoparticles; zinc oxide nanoparticles; titanium oxide nanoparticles; magnesium oxide nanoparticles; iron oxide nanoparticles inorganic nanoparticles; antimicrobial therapy; nanobiocides; gold nanoparticles; silver nanoparticles; copper nanoparticles; zinc oxide nanoparticles; titanium oxide nanoparticles; magnesium oxide nanoparticles; iron oxide nanoparticles
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MDPI and ACS Style

Spirescu, V.A.; Chircov, C.; Grumezescu, A.M.; Vasile, B.Ș.; Andronescu, E. Inorganic Nanoparticles and Composite Films for Antimicrobial Therapies. Int. J. Mol. Sci. 2021, 22, 4595. https://doi.org/10.3390/ijms22094595

AMA Style

Spirescu VA, Chircov C, Grumezescu AM, Vasile BȘ, Andronescu E. Inorganic Nanoparticles and Composite Films for Antimicrobial Therapies. International Journal of Molecular Sciences. 2021; 22(9):4595. https://doi.org/10.3390/ijms22094595

Chicago/Turabian Style

Spirescu, Vera A., Cristina Chircov, Alexandru M. Grumezescu, Bogdan Ș. Vasile, and Ecaterina Andronescu. 2021. "Inorganic Nanoparticles and Composite Films for Antimicrobial Therapies" International Journal of Molecular Sciences 22, no. 9: 4595. https://doi.org/10.3390/ijms22094595

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