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Biomarkers for Cancer Cachexia: A Mini Review

Department of Biochemistry and Genetics, La Trobe University, Bundoora, VIC 3086, Australia
Department of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China
Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, School of Cancer Medicine, La Trobe University, Melbourne, VIC 3084, Australia
Authors to whom correspondence should be addressed.
These authors contributed equally to this work.
Academic Editor: Kwang Seok Ahn
Int. J. Mol. Sci. 2021, 22(9), 4501;
Received: 25 March 2021 / Revised: 14 April 2021 / Accepted: 23 April 2021 / Published: 26 April 2021
(This article belongs to the Special Issue Biomarkers of Colorectal Cancer)
Cancer cachexia is a common condition in many cancer patients, particularly those with advanced disease. Cancer cachexia patients are generally less tolerant to chemotherapies and radiotherapies, largely limiting their treatment options. While the search for treatments of this condition are ongoing, standards for the efficacy of treatments have yet to be developed. Current diagnostic criteria for cancer cachexia are primarily based on loss of body mass and muscle function. However, these criteria are rather limiting, and in time, when weight loss is noticeable, it may be too late for treatment. Consequently, biomarkers for cancer cachexia would be valuable adjuncts to current diagnostic criteria, and for assessing potential treatments. Using high throughput methods such as “omics approaches”, a plethora of potential biomarkers have been identified. This article reviews and summarizes current studies of biomarkers for cancer cachexia. View Full-Text
Keywords: cancer cachexia; biomarkers; cachexia-inducing factors cancer cachexia; biomarkers; cachexia-inducing factors
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MDPI and ACS Style

Cao, Z.; Zhao, K.; Jose, I.; Hoogenraad, N.J.; Osellame, L.D. Biomarkers for Cancer Cachexia: A Mini Review. Int. J. Mol. Sci. 2021, 22, 4501.

AMA Style

Cao Z, Zhao K, Jose I, Hoogenraad NJ, Osellame LD. Biomarkers for Cancer Cachexia: A Mini Review. International Journal of Molecular Sciences. 2021; 22(9):4501.

Chicago/Turabian Style

Cao, Zhipeng, Kening Zhao, Irvin Jose, Nick J. Hoogenraad, and Laura D. Osellame 2021. "Biomarkers for Cancer Cachexia: A Mini Review" International Journal of Molecular Sciences 22, no. 9: 4501.

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