Changes Induced by Mind–Body Intervention Including Epigenetic Marks and Its Effects on Diabetes
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Korea Institute of Brain Science, Seoul 06022, Korea
2
Department of Integrative Health Care, University of Brain Education, Cheonan 31228, Korea
3
Temasek Life Sciences Laboratories, Singapore 117604, Singapore
*
Author to whom correspondence should be addressed.
Academic Editor: Claudia Miele
Int. J. Mol. Sci. 2021, 22(3), 1317; https://doi.org/10.3390/ijms22031317
Received: 28 December 2020
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Revised: 23 January 2021
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Accepted: 26 January 2021
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Published: 28 January 2021
(This article belongs to the Special Issue Epigenetics of Diabetes and Related Complications 2.0)
Studies have evidenced that epigenetic marks associated with type 2 diabetes (T2D) can be inherited from parents or acquired through fetal and early-life events, as well as through lifelong environments or lifestyles, which can increase the risk of diabetes in adulthood. However, epigenetic modifications are reversible, and can be altered through proper intervention, thus mitigating the risk factors of T2D. Mind–body intervention (MBI) refers to interventions like meditation, yoga, and qigong, which deal with both physical and mental well-being. MBI not only induces psychological changes, such as alleviation of depression, anxiety, and stress, but also physiological changes like parasympathetic activation, lower cortisol secretion, reduced inflammation, and aging rate delay, which are all risk factors for T2D. Notably, MBI has been reported to reduce blood glucose in patients with T2D. Herein, based on recent findings, we review the effects of MBI on diabetes and the mechanisms involved, including epigenetic modifications.
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Keywords:
mind–body intervention; epigenetic modification; diabetes
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MDPI and ACS Style
Yang, H.-J.; Koh, E.; Sung, M.-K.; Kang, H. Changes Induced by Mind–Body Intervention Including Epigenetic Marks and Its Effects on Diabetes. Int. J. Mol. Sci. 2021, 22, 1317. https://doi.org/10.3390/ijms22031317
AMA Style
Yang H-J, Koh E, Sung M-K, Kang H. Changes Induced by Mind–Body Intervention Including Epigenetic Marks and Its Effects on Diabetes. International Journal of Molecular Sciences. 2021; 22(3):1317. https://doi.org/10.3390/ijms22031317
Chicago/Turabian StyleYang, Hyun-Jeong, Eugene Koh, Min-Kyu Sung, and Hojung Kang. 2021. "Changes Induced by Mind–Body Intervention Including Epigenetic Marks and Its Effects on Diabetes" International Journal of Molecular Sciences 22, no. 3: 1317. https://doi.org/10.3390/ijms22031317
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