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Review

Non-Coding RNAs as Regulators of Myogenesis and Postexercise Muscle Regeneration

by
Karolina Archacka
,
Maria A. Ciemerych
*,
Anita Florkowska
and
Karolina Romanczuk
Department of Cytology, Institute of Developmental Biology and Biomedical Sciences, Faculty of Biology, University of Warsaw, Miecznikowa 1, 02-096 Warsaw, Poland
*
Author to whom correspondence should be addressed.
All Authors contributed equally to the present work.
Int. J. Mol. Sci. 2021, 22(21), 11568; https://doi.org/10.3390/ijms222111568
Submission received: 15 September 2021 / Revised: 21 October 2021 / Accepted: 23 October 2021 / Published: 26 October 2021
(This article belongs to the Special Issue microRNA Regulatory Network)

Abstract

miRNAs and lncRNAs do not encode proteins, but they play an important role in the regulation of gene expression. They differ in length, biogenesis, and mode of action. In this work, we focus on the selected miRNAs and lncRNAs involved in the regulation of myogenesis and muscle regeneration. We present selected miRNAs and lncRNAs that have been shown to control myogenic differentiation and show that manipulation of their levels could be used to improve myogenic differentiation of various types of stem and progenitor cells. Finally, we discuss how physical activity affects miRNA and lncRNA expression and how it affects muscle well-being.
Keywords: mammals; human; mouse; miRNA; lncRNA; myogenesis; regeneration; training; skeletal muscle mammals; human; mouse; miRNA; lncRNA; myogenesis; regeneration; training; skeletal muscle

Share and Cite

MDPI and ACS Style

Archacka, K.; Ciemerych, M.A.; Florkowska, A.; Romanczuk, K. Non-Coding RNAs as Regulators of Myogenesis and Postexercise Muscle Regeneration. Int. J. Mol. Sci. 2021, 22, 11568. https://doi.org/10.3390/ijms222111568

AMA Style

Archacka K, Ciemerych MA, Florkowska A, Romanczuk K. Non-Coding RNAs as Regulators of Myogenesis and Postexercise Muscle Regeneration. International Journal of Molecular Sciences. 2021; 22(21):11568. https://doi.org/10.3390/ijms222111568

Chicago/Turabian Style

Archacka, Karolina, Maria A. Ciemerych, Anita Florkowska, and Karolina Romanczuk. 2021. "Non-Coding RNAs as Regulators of Myogenesis and Postexercise Muscle Regeneration" International Journal of Molecular Sciences 22, no. 21: 11568. https://doi.org/10.3390/ijms222111568

APA Style

Archacka, K., Ciemerych, M. A., Florkowska, A., & Romanczuk, K. (2021). Non-Coding RNAs as Regulators of Myogenesis and Postexercise Muscle Regeneration. International Journal of Molecular Sciences, 22(21), 11568. https://doi.org/10.3390/ijms222111568

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