Hyaluronic Acid as a Carrier Supports the Effects of Glucocorticoids and Diminishes the Cytotoxic Effects of Local Anesthetics in Human Articular Chondrocytes In Vitro
Abstract
:1. Introduction
2. Results
2.1. Morphological Examination
2.2. XTT Assay
2.3. Flow Cytometry
2.4. Live/Dead Assay
3. Discussion
4. Materials and Methods
4.1. Isolation and Cultivation of Human Chondrocytes
4.2. Treatment of the Cells
4.3. Morphological Examination
4.4. Metabolic Activity
4.5. Flow Cytometry
4.6. Live/Dead Assay
4.7. Statistical Analysis
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Moser, L.B.; Bauer, C.; Jeyakumar, V.; Niculescu-Morzsa, E.-P.; Nehrer, S. Hyaluronic Acid as a Carrier Supports the Effects of Glucocorticoids and Diminishes the Cytotoxic Effects of Local Anesthetics in Human Articular Chondrocytes In Vitro. Int. J. Mol. Sci. 2021, 22, 11503. https://doi.org/10.3390/ijms222111503
Moser LB, Bauer C, Jeyakumar V, Niculescu-Morzsa E-P, Nehrer S. Hyaluronic Acid as a Carrier Supports the Effects of Glucocorticoids and Diminishes the Cytotoxic Effects of Local Anesthetics in Human Articular Chondrocytes In Vitro. International Journal of Molecular Sciences. 2021; 22(21):11503. https://doi.org/10.3390/ijms222111503
Chicago/Turabian StyleMoser, Lukas B., Christoph Bauer, Vivek Jeyakumar, Eugenia-Paulina Niculescu-Morzsa, and Stefan Nehrer. 2021. "Hyaluronic Acid as a Carrier Supports the Effects of Glucocorticoids and Diminishes the Cytotoxic Effects of Local Anesthetics in Human Articular Chondrocytes In Vitro" International Journal of Molecular Sciences 22, no. 21: 11503. https://doi.org/10.3390/ijms222111503
APA StyleMoser, L. B., Bauer, C., Jeyakumar, V., Niculescu-Morzsa, E.-P., & Nehrer, S. (2021). Hyaluronic Acid as a Carrier Supports the Effects of Glucocorticoids and Diminishes the Cytotoxic Effects of Local Anesthetics in Human Articular Chondrocytes In Vitro. International Journal of Molecular Sciences, 22(21), 11503. https://doi.org/10.3390/ijms222111503