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Nanomaterial Shape Influence on Cell Behavior

International Institute “Solution Chemistry of Advanced Materials and Technologies”, ITMO University, 191002 Saint Petersburg, Russia
Author to whom correspondence should be addressed.
Academic Editor: Andrey S. Drozdov
Int. J. Mol. Sci. 2021, 22(10), 5266;
Received: 8 May 2021 / Revised: 13 May 2021 / Accepted: 14 May 2021 / Published: 17 May 2021
(This article belongs to the Special Issue Emerging Roles of Nanomaterials in Biomedical Applications)
Nanomaterials are proven to affect the biological activity of mammalian and microbial cells profoundly. Despite this fact, only surface chemistry, charge, and area are often linked to these phenomena. Moreover, most attention in this field is directed exclusively at nanomaterial cytotoxicity. At the same time, there is a large body of studies showing the influence of nanomaterials on cellular metabolism, proliferation, differentiation, reprogramming, gene transfer, and many other processes. Furthermore, it has been revealed that in all these cases, the shape of the nanomaterial plays a crucial role. In this paper, the mechanisms of nanomaterials shape control, approaches toward its synthesis, and the influence of nanomaterial shape on various biological activities of mammalian and microbial cells, such as proliferation, differentiation, and metabolism, as well as the prospects of this emerging field, are reviewed. View Full-Text
Keywords: nanoparticle; shape; microbial cell; mammalian cell; crystal growth; anisotropic nanoparticle; shape; microbial cell; mammalian cell; crystal growth; anisotropic
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MDPI and ACS Style

Kladko, D.V.; Falchevskaya, A.S.; Serov, N.S.; Prilepskii, A.Y. Nanomaterial Shape Influence on Cell Behavior. Int. J. Mol. Sci. 2021, 22, 5266.

AMA Style

Kladko DV, Falchevskaya AS, Serov NS, Prilepskii AY. Nanomaterial Shape Influence on Cell Behavior. International Journal of Molecular Sciences. 2021; 22(10):5266.

Chicago/Turabian Style

Kladko, Daniil V., Aleksandra S. Falchevskaya, Nikita S. Serov, and Artur Y. Prilepskii 2021. "Nanomaterial Shape Influence on Cell Behavior" International Journal of Molecular Sciences 22, no. 10: 5266.

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