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Potential Synergistic Action of Bioactive Compounds from Plant Extracts against Skin Infecting Microorganisms

1
Department of Biology and Pharmaceutical Botany, Medical University of Lodz, 90-151 Lodz, Poland
2
Department of Economic Informatics, University of Lodz, 90-214 Lodz, Poland
3
Department of Molecular Biotechnology and Genetics, University of Lodz, 90-237 Lodz, Poland
4
Department of Immunopathology, Medical University of Lodz, 90-752 Lodz, Poland
5
Laboratory of Medical Genetics, Faculty of Biology and Environmental Protection, University of Lodz, 90-236 Lodz, Poland
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2020, 21(14), 5105; https://doi.org/10.3390/ijms21145105
Received: 26 June 2020 / Revised: 13 July 2020 / Accepted: 16 July 2020 / Published: 19 July 2020
The skin is an important organ that acts as a physical barrier to the outer environment. It is rich in immune cells such as keratinocytes, Langerhans cells, mast cells, and T cells, which provide the first line of defense mechanisms against numerous pathogens by activating both the innate and adaptive response. Cutaneous immunological processes may be stimulated or suppressed by numerous plant extracts via their immunomodulatory properties. Several plants are rich in bioactive molecules; many of these exert antimicrobial, antiviral, and antifungal effects. The present study describes the impact of plant extracts on the modulation of skin immunity, and their antimicrobial effects against selected skin invaders. Plant products remain valuable counterparts to modern pharmaceuticals and may be used to alleviate numerous skin disorders, including infected wounds, herpes, and tineas. View Full-Text
Keywords: plant extracts; immunological response; skin diseases; modulation of skin immunity; skin pathogens plant extracts; immunological response; skin diseases; modulation of skin immunity; skin pathogens
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MDPI and ACS Style

Sitarek, P.; Merecz-Sadowska, A.; Kowalczyk, T.; Wieczfinska, J.; Zajdel, R.; Śliwiński, T. Potential Synergistic Action of Bioactive Compounds from Plant Extracts against Skin Infecting Microorganisms. Int. J. Mol. Sci. 2020, 21, 5105. https://doi.org/10.3390/ijms21145105

AMA Style

Sitarek P, Merecz-Sadowska A, Kowalczyk T, Wieczfinska J, Zajdel R, Śliwiński T. Potential Synergistic Action of Bioactive Compounds from Plant Extracts against Skin Infecting Microorganisms. International Journal of Molecular Sciences. 2020; 21(14):5105. https://doi.org/10.3390/ijms21145105

Chicago/Turabian Style

Sitarek, Przemysław; Merecz-Sadowska, Anna; Kowalczyk, Tomasz; Wieczfinska, Joanna; Zajdel, Radosław; Śliwiński, Tomasz. 2020. "Potential Synergistic Action of Bioactive Compounds from Plant Extracts against Skin Infecting Microorganisms" Int. J. Mol. Sci. 21, no. 14: 5105. https://doi.org/10.3390/ijms21145105

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