Next Article in Journal
Peanut Sprout Extracts Attenuate Triglyceride Accumulation by Promoting Mitochondrial Fatty Acid Oxidation in Adipocytes
Next Article in Special Issue
Catching a SPY: Using the SpyCatcher-SpyTag and Related Systems for Labeling and Localizing Bacterial Proteins
Previous Article in Journal
Secondary Bile Acids and Short Chain Fatty Acids in the Colon: A Focus on Colonic Microbiome, Cell Proliferation, Inflammation, and Cancer
Previous Article in Special Issue
Relation of the pdxB-usg-truA-dedA Operon and the truA Gene to the Intracellular Survival of Salmonella enterica Serovar Typhimurium
Open AccessReview

Coagulase-Negative Staphylococci Pathogenomics

Service des Maladies Infectieuses et Tropicales, Hôpitaux Universitaires, 67000 Strasbourg, France
Université de Strasbourg, CHRU Strasbourg, Fédération de Médecine Translationnelle de Strasbourg, EA 7290, Virulence Bactérienne Précoce, F-67000 Strasbourg, France
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2019, 20(5), 1215;
Received: 22 January 2019 / Revised: 28 February 2019 / Accepted: 7 March 2019 / Published: 11 March 2019
(This article belongs to the Special Issue Microbial Virulence Factors)
Coagulase-negative Staphylococci (CoNS) are skin commensal bacteria. Besides their role in maintaining homeostasis, CoNS have emerged as major pathogens in nosocomial settings. Several studies have investigated the molecular basis for this emergence and identified multiple putative virulence factors with regards to Staphylococcus aureus pathogenicity. In the last decade, numerous CoNS whole-genome sequences have been released, leading to the identification of numerous putative virulence factors. Koch’s postulates and the molecular rendition of these postulates, established by Stanley Falkow in 1988, do not explain the microbial pathogenicity of CoNS. However, whole-genome sequence data has shed new light on CoNS pathogenicity. In this review, we analyzed the contribution of genomics in defining CoNS virulence, focusing on the most frequent and pathogenic CoNS species: S. epidermidis, S. haemolyticus, S. saprophyticus, S. capitis, and S. lugdunensis. View Full-Text
Keywords: pathogenomics; coagulase-negative staphylococci; virulence factors; whole genome sequencing pathogenomics; coagulase-negative staphylococci; virulence factors; whole genome sequencing
MDPI and ACS Style

Argemi, X.; Hansmann, Y.; Prola, K.; Prévost, G. Coagulase-Negative Staphylococci Pathogenomics. Int. J. Mol. Sci. 2019, 20, 1215.

AMA Style

Argemi X, Hansmann Y, Prola K, Prévost G. Coagulase-Negative Staphylococci Pathogenomics. International Journal of Molecular Sciences. 2019; 20(5):1215.

Chicago/Turabian Style

Argemi, Xavier; Hansmann, Yves; Prola, Kevin; Prévost, Gilles. 2019. "Coagulase-Negative Staphylococci Pathogenomics" Int. J. Mol. Sci. 20, no. 5: 1215.

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

Search more from Scilit
Back to TopTop