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Message in a Bottle: Dialog between Intestine and Skin Modulated by Probiotics

Universidad de Buenos Aires, Facultad de Farmacia y Bioquímica, Cátedra de Inmunología, 1053 Buenos Aires, Argentina
CONICET-Universidad de Buenos Aires, Instituto de Estudios de la Inmunidad Humoral (IDEHU), LIBAP, 1053 Buenos Aires, Argentina
Authors to whom correspondence should be addressed.
Academic Editor: Woo-Sik Jeong
Int. J. Mol. Sci. 2017, 18(6), 1067;
Received: 30 March 2017 / Revised: 10 May 2017 / Accepted: 11 May 2017 / Published: 9 June 2017
(This article belongs to the Special Issue Nutrients and Phytochemicals for Skin Health)
At the beginning, probiotics were used exclusively for gastrointestinal conditions. However, over the years, evidence has shown that probiotics exert systemic effects. In this review article, we will summarize recent reports that postulate probiotic treatment as an efficient one against skin pathologies, such as cancer, allergy, photoaging and skin infections. The focus will be restricted to oral probiotics that could potentially counteract the ultraviolet irradiation-induced skin alterations. Moreover, the possible underlying mechanisms by which probiotics can impact on the gut and exert their skin effects will be reviewed. Furthermore, how the local and systemic immune system is involved in the intestine-cutaneous crosstalk will be analyzed. In conclusion, this article will be divided into three core ideas: (a) probiotics regulate gut homeostasis; (b) gut and skin homeostasis are connected; (c) probiotics are a potentially effective treatment against skin conditions. View Full-Text
Keywords: probiotics; immunomodulation; ultraviolet radiation; skin immune system; photoimmunology probiotics; immunomodulation; ultraviolet radiation; skin immune system; photoimmunology
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MDPI and ACS Style

Friedrich, A.D.; Paz, M.L.; Leoni, J.; González Maglio, D.H. Message in a Bottle: Dialog between Intestine and Skin Modulated by Probiotics. Int. J. Mol. Sci. 2017, 18, 1067.

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