Next Article in Journal
Light/Dark Shifting Promotes Alcohol-Induced Colon Carcinogenesis: Possible Role of Intestinal Inflammatory Milieu and Microbiota
Previous Article in Journal
Secondary Structure Adopted by the Gly-Gly-X Repetitive Regions of Dragline Spider Silk
Previous Article in Special Issue
Extracellular Vesicles in Chronic Obstructive Pulmonary Disease

Exosomes as miRNA Carriers: Formation–Function–Future

Institute for Pathology, University Hospital of Cologne, 50924 Cologne, Germany
Center for Molecular Medicine Cologne, University of Cologne, 50924 Cologne, Germany
Author to whom correspondence should be addressed.
Academic Editors: Gregor Drummen and Suresh Mathivanan
Int. J. Mol. Sci. 2016, 17(12), 2028;
Received: 9 August 2016 / Revised: 25 November 2016 / Accepted: 30 November 2016 / Published: 2 December 2016
(This article belongs to the Special Issue Focus on Extracellular Vesicles)
Exosomes, which are one of the smallest extracellular vesicles released from cells, have been shown to carry different nucleic acids, including microRNAs (miRNAs). miRNAs significantly regulate cell growth and metabolism by posttranscriptional inhibition of gene expression. The rapidly changing understanding of exosomes’ formation and function in delivering miRNAs from cell to cell has prompted us to review current knowledge in exosomal miRNA secretion mechanisms as well as possible therapeutic applications for personalized medicine. View Full-Text
Keywords: extracellular vesicle; exosome; cell metabolism; miRNA extracellular vesicle; exosome; cell metabolism; miRNA
Show Figures

Graphical abstract

MDPI and ACS Style

Yu, X.; Odenthal, M.; Fries, J.W.U. Exosomes as miRNA Carriers: Formation–Function–Future. Int. J. Mol. Sci. 2016, 17, 2028.

AMA Style

Yu X, Odenthal M, Fries JWU. Exosomes as miRNA Carriers: Formation–Function–Future. International Journal of Molecular Sciences. 2016; 17(12):2028.

Chicago/Turabian Style

Yu, Xiaojie, Margarete Odenthal, and Jochen W.U. Fries. 2016. "Exosomes as miRNA Carriers: Formation–Function–Future" International Journal of Molecular Sciences 17, no. 12: 2028.

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

Back to TopTop