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Int. J. Mol. Sci. 2016, 17(10), 1629;

Extracts of Magnolia Species-Induced Prevention of Diabetic Complications: A Brief Review

Departments of Cardiology at the First Hospital of Jilin University, Changchun 130021, China
Kosair Children Hospital Research Institute, Department of Pediatrics, University of Louisville, Louisville, KY 40202, USA
General Hospital of the PLA Rocket Force, Beijing 100088, China
National Center for Cardiovascular Diseases China, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China
Key Laboratory of Radiological Protection and Nuclear Emergency, National Institute for Radiological Protection, China Centers for Disease Control, Beijing 100088, China
The Bioland Biotec Co., Ltd., Zhangjiang Modern Medical Device Park, Pudong, Shanghai 201203, China
Authors to whom correspondence should be addressed.
Academic Editor: William Chi-shing Cho
Received: 20 August 2016 / Revised: 17 September 2016 / Accepted: 21 September 2016 / Published: 24 September 2016
(This article belongs to the Special Issue Diabetic Complications: Pathophysiology, Mechanisms, and Therapies)
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Diabetic complications are the major cause of mortality for the patients with diabetes. Oxidative stress and inflammation have been recognized as important contributors for the development of many diabetic complications, such as diabetic nephropathy, hepatopathy, cardiomyopathy, and other cardiovascular diseases. Several studies have established the anti-inflammatory and oxidative roles of bioactive constituents in Magnolia bark, which has been widely used in the traditional herbal medicines in Chinese society. These findings have attracted various scientists to investigate the effect of bioactive constituents in Magnolia bark on diabetic complications. The aim of this review is to present a systematic overview of bioactive constituents in Magnolia bark that induce the prevention of obesity, hyperglycemia, hyperlipidemia, and diabetic complications, including cardiovascular, liver, and kidney. View Full-Text
Keywords: Magnolia; diabetic complications; oxidative stress Magnolia; diabetic complications; oxidative stress

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Zhao, X.; Li, F.; Sun, W.; Gao, L.; Kim, K.S.; Kim, K.T.; Cai, L.; Zhang, Z.; Zheng, Y. Extracts of Magnolia Species-Induced Prevention of Diabetic Complications: A Brief Review. Int. J. Mol. Sci. 2016, 17, 1629.

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