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Open AccessArticle

Polymer/Iron Oxide Nanoparticle Composites—A Straight Forward and Scalable Synthesis Approach

1
SP, Technical Research Institute of Sweden, Box 5607, SE-114 86 Stockholm, Sweden
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Department of Engineering Sciences, Solid State Physics, Uppsala University, SE-751 21 Uppsala, Sweden
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Acreo Swedish ICT AB, Box 53071, SE-400 14 Göteborg, Sweden
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Institute of Electrical Measurement and Fundamental Electrical Engineering, TU Braunschweig, D-38106 Braunschweig, Germany
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Physikalisch-Technische Bundesanstalt, 10587 Berlin, Germany
*
Author to whom correspondence should be addressed.
Academic Editor: O. Thompson Mefford
Int. J. Mol. Sci. 2015, 16(8), 19752-19768; https://doi.org/10.3390/ijms160819752
Received: 3 July 2015 / Revised: 7 August 2015 / Accepted: 14 August 2015 / Published: 20 August 2015
(This article belongs to the Special Issue Magnetic Nanoparticles 2015)
Magnetic nanoparticle systems can be divided into single-core nanoparticles (with only one magnetic core per particle) and magnetic multi-core nanoparticles (with several magnetic cores per particle). Here, we report multi-core nanoparticle synthesis based on a controlled precipitation process within a well-defined oil in water emulsion to trap the superparamagnetic iron oxide nanoparticles (SPION) in a range of polymer matrices of choice, such as poly(styrene), poly(lactid acid), poly(methyl methacrylate), and poly(caprolactone). Multi-core particles were obtained within the Z-average size range of 130 to 340 nm. With the aim to combine the fast room temperature magnetic relaxation of small individual cores with high magnetization of the ensemble of SPIONs, we used small (<10 nm) core nanoparticles. The performed synthesis is highly flexible with respect to the choice of polymer and SPION loading and gives rise to multi-core particles with interesting magnetic properties and magnetic resonance imaging (MRI) contrast efficacy. View Full-Text
Keywords: iron oxide nanoparticle; multi core; single core; nanocomposite; polymer encapsulation iron oxide nanoparticle; multi core; single core; nanocomposite; polymer encapsulation
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Sommertune, J.; Sugunan, A.; Ahniyaz, A.; Bejhed, R.S.; Sarwe, A.; Johansson, C.; Balceris, C.; Ludwig, F.; Posth, O.; Fornara, A. Polymer/Iron Oxide Nanoparticle Composites—A Straight Forward and Scalable Synthesis Approach. Int. J. Mol. Sci. 2015, 16, 19752-19768.

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