Next Article in Journal
Tangential Flow Ultrafiltration Allows Purification and Concentration of Lauric Acid-/Albumin-Coated Particles for Improved Magnetic Treatment
Next Article in Special Issue
Overexpressing Ferredoxins in Chlamydomonas reinhardtii Increase Starch and Oil Yields and Enhance Electric Power Production in a Photo Microbial Fuel Cell
Previous Article in Journal
The Regulatory Role of Signaling Crosstalk in Hypertrophy of MSCs and Human Articular Chondrocytes
Previous Article in Special Issue
Gene Networks Involved in Hormonal Control of Root Development in Arabidopsis thaliana: A Framework for Studying Its Disturbance by Metal Stress
Open AccessReview

Disease Resistance Gene Analogs (RGAs) in Plants

1
Cereal Research Centre, Agriculture and Agri-Food Canada, Morden, MB R6M 1Y5, Canada
2
National Key Laboratory of Crop Genetics and Germplasm Enhancement, Cytogenetics Institute, Nanjing Agricultural University, Nanjing 210095, China
3
Eastern Cereal and Oilseed Research Centre, Agriculture and Agri-Food Canada, Ottawa, ON K1A 0C6, Canada
4
Plant Science Department, University of Manitoba, Winnipeg, MB R3T 2N6, Canada
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Academic Editor: Marcello Iriti
Int. J. Mol. Sci. 2015, 16(8), 19248-19290; https://doi.org/10.3390/ijms160819248
Received: 20 May 2015 / Revised: 1 August 2015 / Accepted: 6 August 2015 / Published: 14 August 2015
(This article belongs to the Special Issue Plant Molecular Biology)
Plants have developed effective mechanisms to recognize and respond to infections caused by pathogens. Plant resistance gene analogs (RGAs), as resistance (R) gene candidates, have conserved domains and motifs that play specific roles in pathogens’ resistance. Well-known RGAs are nucleotide binding site leucine rich repeats, receptor like kinases, and receptor like proteins. Others include pentatricopeptide repeats and apoplastic peroxidases. RGAs can be detected using bioinformatics tools based on their conserved structural features. Thousands of RGAs have been identified from sequenced plant genomes. High-density genome-wide RGA genetic maps are useful for designing diagnostic markers and identifying quantitative trait loci (QTL) or markers associated with plant disease resistance. This review focuses on recent advances in structures and mechanisms of RGAs, and their identification from sequenced genomes using bioinformatics tools. Applications in enhancing fine mapping and cloning of plant disease resistance genes are also discussed. View Full-Text
Keywords: disease resistance gene; gene mining; nucleotide binding site leucine rich repeat (NBS-LRR); pentatricopeptide repeats (PPRs); resistance gene analog (RGA); receptor like kinase (RLK); receptor like protein (RLP); small RNA (sRNA) disease resistance gene; gene mining; nucleotide binding site leucine rich repeat (NBS-LRR); pentatricopeptide repeats (PPRs); resistance gene analog (RGA); receptor like kinase (RLK); receptor like protein (RLP); small RNA (sRNA)
Show Figures

Graphical abstract

MDPI and ACS Style

Sekhwal, M.K.; Li, P.; Lam, I.; Wang, X.; Cloutier, S.; You, F.M. Disease Resistance Gene Analogs (RGAs) in Plants. Int. J. Mol. Sci. 2015, 16, 19248-19290. https://doi.org/10.3390/ijms160819248

AMA Style

Sekhwal MK, Li P, Lam I, Wang X, Cloutier S, You FM. Disease Resistance Gene Analogs (RGAs) in Plants. International Journal of Molecular Sciences. 2015; 16(8):19248-19290. https://doi.org/10.3390/ijms160819248

Chicago/Turabian Style

Sekhwal, Manoj K.; Li, Pingchuan; Lam, Irene; Wang, Xiue; Cloutier, Sylvie; You, Frank M. 2015. "Disease Resistance Gene Analogs (RGAs) in Plants" Int. J. Mol. Sci. 16, no. 8: 19248-19290. https://doi.org/10.3390/ijms160819248

Find Other Styles

Article Access Map by Country/Region

1
Only visits after 24 November 2015 are recorded.
Search more from Scilit
 
Search
Back to TopTop