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Influence of Regular Exercise on Body Fat and Eating Patterns of Patients with Intermittent Claudication

College of Healthcare Sciences, James Cook University, Townsville, QLD 4811, Australia
School of Health and Wellbeing, University of Southern Queensland, Springfield, QLD 4350, Australia
The Vascular Biology Unit, Queensland Research Centre for Peripheral Vascular Disease, College of Medicine and Dentistry, James Cook University, Townsville, QLD 4811, Australia
Department of Vascular and Endovascular Surgery, the Townsville Hospital, Townsville, QLD 4814, Australia
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Academic Editor: William Chi-shing Cho
Int. J. Mol. Sci. 2015, 16(5), 11339-11354;
Received: 27 November 2014 / Revised: 7 January 2015 / Accepted: 12 January 2015 / Published: 18 May 2015
(This article belongs to the Special Issue Advances in Peripheral Artery Disease)
PDF [699 KB, uploaded 18 May 2015]


This study examined the impact of regular supervised exercise on body fat, assessed via anthropometry, and eating patterns of peripheral arterial disease patients with intermittent claudication (IC). Body fat, eating patterns and walking ability were assessed in 11 healthy adults (Control) and age- and mass-matched IC patients undertaking usual care (n = 10; IC-Con) or supervised exercise (12-months; n = 10; IC-Ex). At entry, all groups exhibited similar body fat and eating patterns. Maximal walking ability was greatest for Control participants and similar for IC-Ex and IC-Con patients. Supervised exercise resulted in significantly greater improvements in maximal walking ability (IC-Ex 148%–170% vs. IC-Con 29%–52%) and smaller increases in body fat (IC-Ex −2.1%–1.4% vs. IC-Con 8.4%–10%). IC-Con patients exhibited significantly greater increases in body fat compared with Control at follow-up (8.4%–10% vs. −0.6%–1.4%). Eating patterns were similar for all groups at follow-up. The current study demonstrated that regular, supervised exercise significantly improved maximal walking ability and minimised increase in body fat amongst IC patients without changes in eating patterns. The study supports the use of supervised exercise to minimize cardiovascular risk amongst IC patients. Further studies are needed to examine the additional value of other lifestyle interventions such as diet modification. View Full-Text
Keywords: body fat; skinfold; walking; claudication; diet; training body fat; skinfold; walking; claudication; diet; training
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Leicht, A.; Crowther, R.; Golledge, J. Influence of Regular Exercise on Body Fat and Eating Patterns of Patients with Intermittent Claudication. Int. J. Mol. Sci. 2015, 16, 11339-11354.

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