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Mouse Plasminogen Has Oxidized Phosphatidylcholine Adducts That Are Not Metabolized by Lipoprotein-Associated Phospholipase A2 under Basal Conditions
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Phospholipases A1

1
Agilent Technologies, Molecular Separations, Santa Clara, CA 95051, USA
2
Centre for Biomolecular Sciences, The North Haugh, The University, St. Andrews, KY16 9ST, Scotland, UK
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2011, 12(1), 588-612; https://doi.org/10.3390/ijms12010588
Received: 15 December 2010 / Revised: 7 January 2011 / Accepted: 11 January 2011 / Published: 18 January 2011
(This article belongs to the Special Issue Phospholipids: Molecular Sciences)
Phospholipase A1 (PLA1) is an enzyme that hydrolyzes phospholipids and produces 2-acyl-lysophospholipids and fatty acids. This lipolytic activity is conserved in a wide range of organisms but is carried out by a diverse set of PLA1 enzymes. Where their function is known, PLA1s have been shown to act as digestive enzymes, possess central roles in membrane maintenance and remodeling, or regulate important cellular mechanisms by the production of various lysophospholipid mediators, such as lysophosphatidylserine and lysophosphatidic acid, which in turn have multiple biological functions. View Full-Text
Keywords: phospholipase A1; phospholipid; lysophospholipid phospholipase A1; phospholipid; lysophospholipid
MDPI and ACS Style

Richmond, G.S.; Smith, T.K. Phospholipases A1. Int. J. Mol. Sci. 2011, 12, 588-612.

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