Antihypertensive Properties of Plant-Based Prebiotics
School of Industrial Technology, Universiti Sains Malaysia, 11800 Penang, Malaysia
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Int. J. Mol. Sci. 2009, 10(8), 3517-3530; https://doi.org/10.3390/ijms10083517
Received: 25 June 2009
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Revised: 14 July 2009
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Accepted: 28 July 2009
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Published: 10 August 2009
(This article belongs to the Special Issue Natural Compounds for the Treatment and Prevention of Metabolic Diseases)
Hypertension is one of the major risk factors for cardiovascular disease. Although various drugs for its treatment have been synthesized, the occurring side effects have generated the need for natural interventions for the treatment and prevention of hypertension. Dietary intervention such as the administration of prebiotics has been seen as a highly acceptable approach. Prebiotics are indigestible food ingredients that bypass digestion and reach the lower gut as substrates for indigenous microflora. Most of the prebiotics used as food adjuncts, such as inulin, fructooligosaccharides, dietary fiber and gums, are derived from plants. Experimental evidence from recent studies has suggested that prebiotics are capable of reducing and preventing hypertension. This paper will discuss some of the mechanisms involved, the evidence generated from both in-vitro experiments and in-vivo trials and some controversial findings that are raised.
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Keywords:
prebiotics; mechanism; evidence; controversies; inulin; fos; fiber; gum
This is an open access article distributed under the Creative Commons Attribution License.
MDPI and ACS Style
Yeo, S.-K.; Ooi, L.-G.; Lim, T.-J.; Liong, M.-T. Antihypertensive Properties of Plant-Based Prebiotics. Int. J. Mol. Sci. 2009, 10, 3517-3530. https://doi.org/10.3390/ijms10083517
AMA Style
Yeo S-K, Ooi L-G, Lim T-J, Liong M-T. Antihypertensive Properties of Plant-Based Prebiotics. International Journal of Molecular Sciences. 2009; 10(8):3517-3530. https://doi.org/10.3390/ijms10083517
Chicago/Turabian StyleYeo, Siok-Koon, Lay-Gaik Ooi, Ting-Jin Lim, and Min-Tze Liong. 2009. "Antihypertensive Properties of Plant-Based Prebiotics" International Journal of Molecular Sciences 10, no. 8: 3517-3530. https://doi.org/10.3390/ijms10083517
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