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Model Protocells from Single-Chain Lipids

Department of Chemistry & Biochemistry, University of Denver, Denver, CO 80208, USA
Int. J. Mol. Sci. 2009, 10(3), 835-843;
Received: 6 February 2009 / Revised: 23 February 2009 / Accepted: 26 February 2009 / Published: 2 March 2009
(This article belongs to the Special Issue Origin of Life)
PDF [101 KB, uploaded 19 June 2014]


Significant progress has been made in the construction of laboratory models of protocells. Most frequently the developed vesicle systems utilize single-chain lipids rather than the double-chain lipids typically found in biological membranes. Although single-chain lipids yield less robust vesicles, their dynamic characteristics are highly exploitable for protocellular functions. Herein the advantages of using single-chain lipids in the construction of protocells are discussed. View Full-Text
Keywords: Origin of life; prebiotic; vesicle; synthetic biology; fatty acid Origin of life; prebiotic; vesicle; synthetic biology; fatty acid
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Mansy, S.S. Model Protocells from Single-Chain Lipids. Int. J. Mol. Sci. 2009, 10, 835-843.

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