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Molecules 2004, 9(3), 158-163;

The Synthesis of Dicationic Extended Bis-Benzimidazoles

Department of Chemistry Georgia State University, Atlanta, Georgia 30303, USA
Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, Alabama 36849, USA
Author to whom correspondence should be addressed.
Received: 17 January 2004 / Revised: 26 January 2004 / Accepted: 27 January 2004 / Published: 28 February 2004
(This article belongs to the Special Issue Biologically Relevant Heterocyclic Compounds)
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The synthesis of extended dicationic bis-benzimidazoles starting from trans-1,2-bis(4-cyanophenyl)ethene and trans-1,2-bis(4-cyanophenyl)cyclopropane is reported. The target diamidines show significant in vitro activity against B. subtilis. View Full-Text
Keywords: DIBAL reduction; benzimidazoles; amidines; Bacillus subtilis. DIBAL reduction; benzimidazoles; amidines; Bacillus subtilis.

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Kang, Z.; Dykstra, C.C.; Boykin, D.W. The Synthesis of Dicationic Extended Bis-Benzimidazoles. Molecules 2004, 9, 158-163.

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