Next Article in Journal
Substituted Pyrroles
Previous Article in Journal
A Short Review on Cardiotonic Steroids and Their Aminoguanidine Analogues
Article Menu

Export Article

Open AccessArticle
Molecules 2000, 5(1), 82-88;

A High-Yielding Synthesis of the Naturally Occurring Antitumour Agent Irisquinone

Cancer Research Campaign Section of Drug Development and Imaging, Paterson Institute for Cancer Research, Christie Hospital NHS Trust, Wilmslow Road, Manchester, M20 4BX, UK
Department of Biological Sciences, Salford University, Salford, M5 4WT, UK
Author to whom correspondence should be addressed.
Received: 2 November 1999 / Accepted: 12 January 2000 / Published: 18 January 2000
Full-Text   |   PDF [37 KB, uploaded 18 June 2014]   |  


A short, high-yielding synthesis of the antitumour agent irisquinone (1) is described. The key steps are the palladium catalysed coupling reaction of dec-9-yn-1-ol with iodide (2) to form alkyne (3) and the Fremy’s salt oxidation of phenol (7). View Full-Text
Keywords: Irisquinone; antitumour; Chinese medicine Irisquinone; antitumour; Chinese medicine

Scheme 1

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Share & Cite This Article

MDPI and ACS Style

Hadfield, J.A.; McGown, A.T.; Butler, J. A High-Yielding Synthesis of the Naturally Occurring Antitumour Agent Irisquinone. Molecules 2000, 5, 82-88.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top