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Review

Antiviral Activities of Algal-Based Sulfated Polysaccharides

1
Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Gadjah Mada, Bulaksumur, Yogyakarta 55281, Indonesia
2
Research Center for Biotechnology, Research Organization for Life Sciences, National Research and Innovation Agency (BRIN), Jalan Raya Jakarta-Bogor KM. 46, Cibinong 16911, Indonesia
3
Faculty of Marine Science and Fisheries, Hasanuddin University, Makassar 90245, Indonesia
4
Center of Excellent for Development and Utilization of Seaweed, Hasanuddin University, Makassar 90245, Indonesia
*
Authors to whom correspondence should be addressed.
Academic Editors: Jean-Marc Sabatier and Jacques Fantini
Molecules 2022, 27(4), 1178; https://doi.org/10.3390/molecules27041178
Received: 31 December 2021 / Revised: 1 February 2022 / Accepted: 2 February 2022 / Published: 9 February 2022
(This article belongs to the Special Issue Bioactive Molecules in SARS-CoV-2 Infection and Covid-19)
An antiviral agent is urgently needed based on the high probability of the emergence and re-emergence of future viral disease, highlighted by the recent global COVID-19 pandemic. The emergence may be seen in the discovery of the Alpha, Beta, Gamma, Delta, and recently discovered Omicron variants of SARS-CoV-2. The need for strategies besides testing and isolation, social distancing, and vaccine development is clear. One of the strategies includes searching for an antiviral agent that provides effective results without toxicity, which is well-presented by significant results for carrageenan nasal spray in providing efficacy against human coronavirus-infected patients. As the primary producer of sulfated polysaccharides, marine plants, including macro- and microalgae, offer versatility in culture, production, and post-isolation development in obtaining the needed antiviral agent. Therefore, this review will describe an attempt to highlight the search for practical and safe antiviral agents from algal-based sulfated polysaccharides and to unveil their features for future development. View Full-Text
Keywords: sulfated polysaccharides; macroalgae; microalgae; antiviral agents sulfated polysaccharides; macroalgae; microalgae; antiviral agents
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MDPI and ACS Style

Panggabean, J.A.; Adiguna, S.P.; Rahmawati, S.I.; Ahmadi, P.; Zainuddin, E.N.; Bayu, A.; Putra, M.Y. Antiviral Activities of Algal-Based Sulfated Polysaccharides. Molecules 2022, 27, 1178. https://doi.org/10.3390/molecules27041178

AMA Style

Panggabean JA, Adiguna SP, Rahmawati SI, Ahmadi P, Zainuddin EN, Bayu A, Putra MY. Antiviral Activities of Algal-Based Sulfated Polysaccharides. Molecules. 2022; 27(4):1178. https://doi.org/10.3390/molecules27041178

Chicago/Turabian Style

Panggabean, Jonathan A., Sya’ban P. Adiguna, Siti I. Rahmawati, Peni Ahmadi, Elmi N. Zainuddin, Asep Bayu, and Masteria Y. Putra. 2022. "Antiviral Activities of Algal-Based Sulfated Polysaccharides" Molecules 27, no. 4: 1178. https://doi.org/10.3390/molecules27041178

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